Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 3/20 | 0.53 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.46 |
| ▸ | HTRA1 | Q92743 | 4/20 | 0.46 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.45 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.45 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.45 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8364492 | 0.92 | CTSD (0.48) | CTSDCMA1 | |
| SCHEMBL9421813 | 0.92 | MME (0.48) | CMA1MMEACECPA1ACE2 | |
| SCHEMBL8945318 | 0.91 | CTSD (0.46) | CTSDCTSSCTSKCMA1MME | |
| SCHEMBL8041651 | 0.90 | MME (0.47) | CTSDCTSSCTSKCMA1MME | |
| SCHEMBL8945590 | 0.90 | CTSD (0.44) | CTSDCTSSCTSKCMA1ACE | |
| SCHEMBL8945610 | 0.88 | MME (0.45) | CTSDCTSSCTSKCMA1MME | |
| SCHEMBL7422223 | 0.88 | ITGB3 (0.45) | CTSDCTSSCTSKCMA1MME | |
| SCHEMBL7933938 | 0.87 | CTSD (0.47) | CTSDCTSSCTSKCMA1MME | |
| SCHEMBL8945566 | 0.87 | CTSD (0.47) | CTSDCTSSCTSKCMA1MME | |
| SCHEMBL7416869 | 0.86 | MME (0.43) | CTSDCTSSCTSKCMA1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716973-A | ADMINISTERING DIFLUORO STATONE ANALOGS | MERRELL PHARMACEUTICALS INC. (US) | 1998-02-10 | — | — | US | disclosed |
| EP-0565631-B1 | ANTI-VIRAL COMPOUNDS | MERRELL PHARMA INC (US) | 1996-09-18 | — | — | EP | disclosed |