Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.36 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.36 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8736070 | 0.87 | PDK1 (0.37) | ALDH1A1PDK1PDK2PDK3PDK4 | |
| SCHEMBL8734794 | 0.84 | PDK1 (0.40) | ALDH1A1PDK1PDK2PDK3PDK4 | |
| SCHEMBL8736207 | 0.83 | ALDH1A1 (0.57) | ALDH1A1KCNMA1ARCYP3A4HPGD | |
| SCHEMBL11404398 | 0.81 | APP (0.41) | ALDH1A1APPKCNMA1CYP3A4LMNA | |
| SCHEMBL8936699 | 0.80 | MAPT (0.51) | ALDH1A1PDK1PDK2PDK3PDK4 | |
| SCHEMBL1800375 | 0.75 | PDK1 (0.42) | ALDH1A1PDK1PDK2PDK3PDK4 | |
| SCHEMBL16198090 | 0.74 | KCNMA1 (0.38) | ALDH1A1APPKCNMA1CYP3A4HPGD | |
| SCHEMBL11850749 | 0.74 | ALDH1A1 (0.37) | ALDH1A1CYP3A4TSHREPAS1 | |
| SCHEMBL13592935 | 0.73 | CXCR2 (0.46) | ALDH1A1PDK1PDK2PDK3PDK4 | |
| SCHEMBL8736181 | 0.73 | ALDH1A1 (0.55) | ALDH1A1PDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821953-A2 | Anticoccidial methods and feedstuffs | ELI LILLY AND COMPANY (US) | 1998-02-04 | — | — | EP | disclosed |