Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.47 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.47 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | PHGDH | O43175 | 1/20 | 0.46 |
| ▸ | IDH1 | O75874 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4129918 | 0.85 | L3MBTL1 (0.54) | MAPTALDH1A1L3MBTL1KDM4EMAPK1 | |
| SCHEMBL29451808 | 0.82 | PDK1 (0.50) | MAPTALDH1A1TSHRPDK1PDK2 | |
| SCHEMBL26125825 | 0.81 | ALDH1A1 (0.56) | MAPTALDH1A1L3MBTL1KDM4EMAPK1 | |
| SCHEMBL8734794 | 0.81 | PDK1 (0.40) | ALDH1A1TSHRPDK1PDK2PDK3 | |
| SCHEMBL1551583 | 0.80 | PDE7A (0.64) | MAPTALDH1A1L3MBTL1KDM4EMAPK1 | |
| SCHEMBL3840810 | 0.80 | MAPT (0.54) | MAPTALDH1A1L3MBTL1KDM4EMAPK1 | |
| SCHEMBL8736796 | 0.80 | ALDH1A1 (0.40) | MAPTALDH1A1KDM4ETSHRPDK1 | |
| SCHEMBL6296282 | 0.80 | NPC1 (0.52) | MAPTALDH1A1MAPK1PDK1PDK2 | |
| SCHEMBL6303134 | 0.79 | PDK1 (0.47) | MAPTALDH1A1MAPK1TSHRPDK1 | |
| SCHEMBL5103222 | 0.78 | PDK1 (0.71) | MAPTALDH1A1L3MBTL1PDK1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587392-A | THERAPY FOR ESTROGEN DEPENDENT DISEASES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0684235-A1 | Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |