Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12848675 | 0.83 | ALDH1A1 (0.54) | MAPTGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL29037852 | 0.81 | KDM4E (0.50) | MAPTLMNAALDH1A1SMN1; SMN2HTR3E | |
| SCHEMBL12128903 | 0.81 | HPGD (0.52) | MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8737585 | 0.81 | HTR3A (0.56) | ALDH1A1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL28239107 | 0.80 | NCF1 (0.45) | MAPTALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL8737447 | 0.79 | ALDH1A1 (0.48) | LMNAALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL29557426 | 0.78 | KDR (0.53) | MAPTLMNAGAAALDH1A1KDR | |
| SCHEMBL233938 | 0.78 | KDR (0.53) | MAPTLMNAGAAALDH1A1KDR | |
| SCHEMBL12464187 | 0.77 | ALDH1A1 (0.48) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4331979 | 0.76 | KDR (0.51) | MAPTLMNAGAAALDH1A1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120129870-A1 | PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129870-A1 | PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | NPY2R, NPY1R, NPY5R | MAPT 3568/4885LMNA 3751/4885GAA 2549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.