Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.47 |
| ▸ | CDC42BPB | Q9Y5S2 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 4/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.39 |
| ▸ | BMPR1A | P36894 | 2/20 | 0.39 |
| ▸ | ACVR1B | P36896 | 2/20 | 0.39 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14035954 | 0.83 | MAPK1 (0.51) | ALDH1A1ROCK2ROCK1CDC42BPBLMNA | |
| SCHEMBL8736858 | 0.79 | MAPT (0.43) | ALDH1A1LMNAOPRL1HTR3EHTR3B | |
| SCHEMBL8737585 | 0.79 | HTR3A (0.56) | ALDH1A1HTR6HTR3EHTR3BCYP1A2 | |
| SCHEMBL3636287 | 0.78 | GAA (0.56) | ALDH1A1ROCK2ROCK1CDC42BPBDRD2 | |
| SCHEMBL20883839 | 0.78 | HTR3A (0.52) | ALDH1A1ROCK2ROCK1CDC42BPBDRD2 | |
| SCHEMBL654285 | 0.78 | ALDH1A1 (0.57) | ALDH1A1ROCK2ROCK1CDC42BPBDRD2 | |
| SCHEMBL2997329 | 0.78 | ALDH1A1 (0.57) | ALDH1A1ROCK2ROCK1CDC42BPBDRD2 | |
| Hydrochloric Acid SCHEMBL23302956 | 0.76 | ALDH1A1 (0.56) | ALDH1A1ROCK2ROCK1CDC42BPBDRD2 | |
| Hydrochloric Acid SCHEMBL29882494 | 0.76 | ALDH1A1 (0.56) | ALDH1A1ROCK2ROCK1CDC42BPBDRD2 | |
| SCHEMBL28239107 | 0.76 | NCF1 (0.45) | ALDH1A1NCF1HTR3EHTR3BHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120129870-A1 | PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | JANSSEN PHARMACEUTICA NV (BE) | 2012-05-24 | — | — | US | disclosed |
| US-20090099199-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129870-A1 | PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR | NPY2R, NPY1R, NPY5R | ALDH1A1 4338/4885ROCK2 263/4885ROCK1 749/4885 |
| US-20090099199-A1 | ORGANIC COMPOUNDS | SLCO4C1, SLC10A6, SLCO1B1 | ALDH1A1 47/4885ROCK2 3971/4885ROCK1 2941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.