Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6058559 | 0.79 | KDM1A (0.41) | KDM1A | |
| SCHEMBL8736634 | 0.73 | KDM1A (0.36) | KDM1A | |
| SCHEMBL5608796 | 0.69 | KDM1A (0.33) | KDM1A | |
| SCHEMBL8737332 | 0.69 | KDM1A (0.33) | KDM1A | |
| SCHEMBL8735310 | 0.59 | KDM1A (0.33) | KDM1A | |
| SCHEMBL7398947 | 0.57 | KDM1A (0.39) | KDM1A | |
| SCHEMBL8735355 | 0.57 | MAPT (0.34) | — | |
| SCHEMBL28749556 | 0.56 | ALDH1A1 (0.54) | — | |
| SCHEMBL1126802 | 0.56 | ALDH1A1 (0.50) | — | |
| Methyl Alcohol SCHEMBL8745831 | 0.55 | LPL (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833472-A2 | USE OF CERTAIN BIPHENYL COMPOUNDS FOR PROTECTION OF NEURONS AND OLIGODENDROCYTES IN THE TREATMENT OF MULTIPLE SCLEROSIS (MS) | Aventis Pharmaceuticals Inc. (US) | 2007-09-19 | — | — | EP | claimed |
| WO-2006073726-A2 | USE OF CERTAIN BIPHENYL COMPOUNDS FOR PROTECTION OF NEURONS AND OLIGODENDROCYTES IN THE TREATMENT OF MULTIPLE SCLEROSIS (MS) | AVENTIS PHARMACEUTICALS INC. (US) | 2006-07-13 | — | — | WO | claimed |