Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KLK7 | P49862 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28888139 | 0.83 | GABBR2 (0.39) | MAPK1CRHBPCRHR2SMN1; SMN2POLB | |
| SCHEMBL11223311 | 0.81 | CYP2D6 (0.42) | ALDH1A1MAPK1TSHRHTTPOLB | |
| SCHEMBL27801809 | 0.80 | POLB (0.41) | MAPK1POLBNPSR1L3MBTL1GAA | |
| SCHEMBL5932732 | 0.79 | POLB (0.40) | MAPK1POLBNPSR1L3MBTL1GAA | |
| SCHEMBL11217782 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MAPK1TRPA1GSK3BHIF1A | |
| SCHEMBL5933483 | 0.77 | POLB (0.39) | MAPK1POLBNPSR1L3MBTL1GAA | |
| SCHEMBL28852545 | 0.77 | NPSR1 (0.44) | MAPK1SMN1; SMN2POLBNPSR1L3MBTL1 | |
| SCHEMBL9217887 | 0.77 | CRHBP (0.53) | ALDH1A1MAPK1TRPA1GSK3BHIF1A | |
| SCHEMBL9800752 | 0.75 | POLB (0.35) | MAPK1CRHBPCRHR2HTTPOLB | |
| SCHEMBL4730584 | 0.75 | ESR1 (0.40) | MAPK1SMN1; SMN2POLBNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0824096-A2 | Process for the preparation of halogenated (meth)acrylic esters and poly (meth) arcylates obtained with said (meth)acrylic esters | Akzo Nobel N.V. (NL) | 1998-02-18 | — | — | EP | disclosed |