Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYBB | P04839 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16126076 | 0.85 | PRMT5 (0.56) | PRMT5MAPTMAPK1RAB9AADORA3 | |
| SCHEMBL8404385 | 0.80 | ADORA3 (0.44) | MAPTMAPK1RAB9AADORA3ADORA2A | |
| SCHEMBL21976569 | 0.78 | P2RX3 (0.42) | PRMT5MAPTMETCYP1A2 | |
| SCHEMBL1148207 | 0.77 | ALDH1A1 (0.50) | MAPTMAPK1RAB9AADORA3ADORA2A | |
| SCHEMBL28250831 | 0.77 | ADORA3 (0.42) | MAPTMAPK1RAB9AADORA3ADORA2A | |
| SCHEMBL1042567 | 0.77 | ACHE (0.57) | MAPTRAB9AALDH1A1NCF1PDPK1 | |
| SCHEMBL1148051 | 0.77 | ADORA3 (0.42) | MAPTMAPK1RAB9AADORA3ADORA2A | |
| SCHEMBL28250830 | 0.77 | ADORA3 (0.42) | MAPTMAPK1RAB9AADORA3ADORA2A | |
| SCHEMBL1042750 | 0.77 | MCHR1 (0.57) | MAPTMAPK1RAB9AALDH1A1PDPK1 | |
| SCHEMBL1147899 | 0.74 | RAB9A (0.42) | MAPTMAPK1RAB9AADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796800-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2017-10-24 | — | — | US | claimed |
| US-20160108153-A1 | PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORPORATION (JP) | 2016-04-21 | — | — | US | claimed |
| CN-103154044-B | Process for producing polydienes | BRIDGESTONE CO.,LTD. (JP) | 2016-02-17 | — | — | CN | claimed |
| US-9249244-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2016-02-02 | — | — | US | claimed |
| EP-2619233-A1 | PROCESS FOR PRODUCING POLYDIENES | Bridgestone Corporation (JP) | 2013-07-31 | — | — | EP | claimed |
| CN-103154044-A | Process for producing polydienes | BRIDGESTONE CORP | 2013-06-12 | — | — | CN | claimed |
| WO-2012040026-A1 | PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORPORATION (JP) | 2012-03-29 | — | — | WO | claimed |
| CN-105646754-B | Method for producing polydiene | 株式会社普利司通 | 2018-08-07 | — | — | CN | disclosed |
| CN-108129590-A | Use the conjugated diene bulk polymerization of the antigravity system based on nickel | 株式会社普利司通 | 2018-06-08 | — | — | CN | disclosed |
| US-9796800-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2017-10-24 | — | — | US | disclosed |
| EP-2658886-B1 | BULK POLYMERIZATION OF CONJUGATED DIENES USING A NICKEL-BASED CATALYST SYSTEM | BRIDGESTONE CORP (JP) | 2017-03-08 | — | — | EP | disclosed |
| US-9546227-B2 | Bulk polymerization of conjugated dienes using a nickel-based catalyst system | BRIDGESTONE CORPORATION (JP) | 2017-01-17 | — | — | US | disclosed |
| EP-2658887-B1 | BULK POLYMERIZATION OF CONJUGATED DIENES USING A NICKEL-BASED CATALYST SYSTEM | BRIDGESTONE CORP (JP) | 2016-11-16 | — | — | EP | disclosed |
| CN-103339157-A | Bulk polymerization of conjugated dienes using a nickel-based catalyst system | BRIDGESTONE CORP | 2013-10-02 | — | — | CN | disclosed |
| CN-103328519-A | Bulk polymerization of conjugated dienes using nickel-based catalyst systems | BRIDGESTONE CORP | 2013-09-25 | — | — | CN | disclosed |
| EP-2619233-A1 | PROCESS FOR PRODUCING POLYDIENES | Bridgestone Corporation (JP) | 2013-07-31 | — | — | EP | disclosed |
| CN-103154044-A | Process for producing polydienes | BRIDGESTONE CORP | 2013-06-12 | — | — | CN | disclosed |
| WO-2012092547-A1 | BULK POLYMERIZATION OF CONJUGATED DIENES USING A NICKEL-BASED CATALYST SYSTEM | BRIDGESTONE CORPORATION (JP) | 2012-07-05 | — | — | WO | disclosed |
| WO-2012092551-A1 | BULK POLYMERIZATION OF CONJUGATED DIENES USING A NICKEL-BASED CATALYST SYSTEM | BRIDGESTONE CORPORATION (JP) | 2012-07-05 | — | — | WO | disclosed |
| WO-2012040026-A1 | PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORPORATION (JP) | 2012-03-29 | — | — | WO | disclosed |