SCHEMBL87384

SCHEMBL87384

CC1Cc2c(NC(=O)c3cccnc3Cl)cccc2C1(C)C

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.51
▸ KDM4E B2RXH2 2/20 0.50
▸ RXFP1 Q9HBX9 1/20 0.50
▸ L3MBTL1 Q9Y468 1/20 0.50
▸ ALDH1A1 P00352 6/20 0.48
▸ SMN1; SMN2 Q16637 4/20 0.48
▸ HTT P42858 3/20 0.48
▸ HPGD P15428 2/20 0.48
▸ TDP1 Q9NUW8 1/20 0.47
▸ KMT2A Q03164 2/20 0.44
▸ MAPT P10636 1/20 0.43
▸ PTPN11 Q06124 1/20 0.43
▸ NPC1 O15118 1/20 0.43
▸ MEN1 O00255 1/20 0.42
▸ MDM4 O15151 1/20 0.41
▸ MITF O75030 1/20 0.41
▸ MDM2 Q00987 1/20 0.41
▸ ATM Q13315 1/20 0.41
▸ GPR35 Q9HC97 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28459124 0.84 ALDH1A1 (0.42) GAAKDM4ERXFP1L3MBTL1ALDH1A1
SCHEMBL9651972 0.80 KDM4E (0.52) GAAKDM4ERXFP1L3MBTL1ALDH1A1
SCHEMBL29419098 0.78 KDM4E (0.50) GAAKDM4ERXFP1L3MBTL1ALDH1A1
SCHEMBL68209 0.78 KDM4E (0.50) GAAKDM4ERXFP1L3MBTL1ALDH1A1
SCHEMBL29445394 0.78 KDM4E (0.50) GAAKDM4ERXFP1L3MBTL1ALDH1A1
SCHEMBL23093931 0.75 ATM (0.54) GAAALDH1A1SMN1; SMN2KMT2AMAPT
SCHEMBL29060943 0.75 ATM (0.54) GAAALDH1A1SMN1; SMN2KMT2AMAPT
SCHEMBL8299753 0.74 TDP1 (0.68) GAAKDM4ERXFP1L3MBTL1ALDH1A1
SCHEMBL17374912 0.74 KDM4E (0.47) GAAKDM4ERXFP1L3MBTL1ALDH1A1
SCHEMBL9844353 0.73 TDP1 (0.63) GAAKDM4ERXFP1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108658816-B N-aryl amidine substituted trifluoroethyl sulfide derivatives useful as acaricides and insecticides 拜尔农作物科学股份公司 2023-05-02 — — CN claimed
WO-2020206518-A1 MULTIPURPOSE BIOLOGICAL COMPOSITIONS AGRIVALLE BRASIL INDUSTRIA E COMÉRCIO DE PRODUTOS AGRÍCOLAS LTDA (BR) 2020-10-15 — — WO claimed
US-20150208666-A1 Method for Increasing the Vigor and/or Crop Yield of Agricultural Plants Under Essentially Non-Existent Pathogen Pressure BAYER CROPSCIENCE LP 2015-07-30 — — US claimed
CN-118265453-A Protein aggregation inhibiting compounds for plant disease control 马克斯·普朗克科学促进学会 2024-06-28 — — CN disclosed
CN-114617136-B Microbial compositions for promoting plant growth and treating plant diseases and methods of use FMC有限公司 2024-03-22 — — CN disclosed
CN-110475776-B Tricyclic carboxamides for combating arthropods 拜耳作物科学股份公司 2024-03-19 — — CN disclosed
CN-113329632-B Fatty acid derivatives for improving the efficacy of agrochemically active substances 科莱恩国际有限公司 2023-10-27 — — CN disclosed
CN-116828985-A Storage-stable aqueous suspension concentrates 拜耳公司 2023-09-29 — — CN disclosed
CN-116709923-A Copper-based fungicide composition 阿达玛马克西姆有限公司 2023-09-05 — — CN disclosed
CN-116685202-A Dithiocarbamate fungicide composition 阿达玛马克西姆有限公司 2023-09-01 — — CN disclosed
CN-116250545-A Bacillus amyloliquefaciens FCC1256 compositions and methods of controlling plant pathogens FMC公司 2023-06-13 — — CN disclosed
CN-116075223-A Aqueous compositions of dithiocarbamate fungicides 阿达马蒂斯有限公司 2023-05-05 — — CN disclosed
CN-108658816-B N-aryl amidine substituted trifluoroethyl sulfide derivatives useful as acaricides and insecticides 拜尔农作物科学股份公司 2023-05-02 — — CN disclosed
CN-113271780-B Bacillus amyloliquefaciens FCC1256 composition and method for controlling plant pathogens FMC公司 2023-03-28 — — CN disclosed
CN-114158553-B Novel pesticide preparation and preparation method thereof 南开沧州渤海新区绿色化工研究有限公司 2023-02-21 — — CN disclosed
CN-115633698-A Compositions and methods for improving plant growth FMC有限公司 2023-01-24 — — CN disclosed
US-8461349-B2 Fungicidal active substance combinations containing trifloxystrobin BAYER CROPSCIENCE AG (DE) 2013-06-11 — — US disclosed
US-20120136032-A1 Fungicidal Active Substance Combinations Containing Trifloxystrobin BAYER CROPSCIENCE AG (DE) 2012-05-31 — — US disclosed
US-8129558-B2 Pesticide naphthyloxy substituted phenylamidine derivatives BAYER CROPSCIENCE AG (DE) 2012-03-06 — — US disclosed
US-20090143431-A1 PESTICIDE NAPHTHYLOXY SUBSTITUTED PHENYLAMIDINE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2009-06-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120136032-A1 Fungicidal Active Substance Combinations Containing Trifloxystrobin TREH, MGAM, THOP1 GAA 217/4885KDM4E 1430/4885RXFP1 1466/4885
US-20090143431-A1 PESTICIDE NAPHTHYLOXY SUBSTITUTED PHENYLAMIDINE DERIVATIVES DDT, PNPO, PFAS GAA 956/4885KDM4E 812/4885RXFP1 4774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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