Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ODC1 | P11926 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA3 | P07451 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA6 | P23280 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6749221 | 1.00 | ODC1 (0.53) | ODC1NFKB1CA12CA1CA2 | |
| SCHEMBL64270 | 1.00 | ODC1 (0.53) | ODC1NFKB1CA12CA1CA2 | |
| Ethylenediamine SCHEMBL10796877 | 1.00 | ODC1 (0.53) | ODC1NFKB1CA12CA1CA2 | |
| SCHEMBL18166488 | 1.00 | ODC1 (0.53) | ODC1NFKB1CA12CA1CA2 | |
| SCHEMBL9812321 | 0.96 | NFKB1 (0.50) | ODC1NFKB1CA12CA1CA2 | |
| SCHEMBL816340 | 0.96 | ODC1 (0.50) | ODC1NFKB1CA12CA1CA2 | |
| SCHEMBL9748007 | 0.96 | ODC1 (0.50) | ODC1NFKB1CA12CA1CA2 | |
| SCHEMBL17188316 | 0.96 | ODC1 (0.50) | ODC1NFKB1CA12CA1CA2 | |
| SCHEMBL2311533 | 0.96 | ODC1 (0.50) | ODC1NFKB1CA12CA1CA2 | |
| SCHEMBL1344404 | 0.96 | ODC1 (0.50) | ODC1NFKB1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180177881-A1 | Multicomponent Degradable Cationic Polymers | THE JOHNS HOPKINS UNIVERSITY | 2018-06-28 | — | — | US | disclosed |
| US-9884118-B2 | Multicomponent degradable cationic polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2018-02-06 | — | — | US | disclosed |
| US-20180028455-A1 | PEPTIDE/PARTICLE DELIVERY SYSTEMS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-02-01 | — | — | US | disclosed |
| US-20170143639-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-05-25 | — | — | US | disclosed |
| US-20150273071-A1 | Bioreducible Poly (Beta-Amino Ester)s For siRNA Delivery | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-10-01 | — | — | US | disclosed |
| US-20150272900-A1 | Layer-By-Layer Approach to Co-Deliver DNA and siRNA via AuNPs: A Potential Platform for Modifying Release Kinetics | THE JOHNS HOPKINS UNIVERSITY | 2015-10-01 | — | — | US | disclosed |
| US-20150250881-A1 | Multicomponent Degradable Cationic Polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-09-10 | — | — | US | disclosed |
| US-8992991-B2 | Multicomponent degradable cationic polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-03-31 | — | — | US | disclosed |
| US-20140294909-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2014-10-02 | — | — | US | disclosed |
| US-20120128782-A1 | Multicomponent Degradable Cationic Polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150272900-A1 | Layer-By-Layer Approach to Co-Deliver DNA and siRNA via AuNPs: A Potential Platform for Modifying Release Kinetics | DNMT3L, DBNL, HNRNPL | ODC1 3657/4885NFKB1 4012/4885CA12 1280/4885 |
| US-20150250881-A1 | Multicomponent Degradable Cationic Polymers | PEF1, FIBP, PARN | ODC1 625/4885NFKB1 2868/4885CA12 4148/4885 |
| US-20180177881-A1 | Multicomponent Degradable Cationic Polymers | PEF1, FIBP, PARN | ODC1 625/4885NFKB1 2868/4885CA12 4148/4885 |
| US-20170143639-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | HNRNPL, HNRNPLL, ACSL3 | ODC1 3530/4885NFKB1 4181/4885CA12 943/4885 |
| US-20150273071-A1 | Bioreducible Poly (Beta-Amino Ester)s For siRNA Delivery | AARS1, SLC43A1, PHAX | ODC1 3141/4885NFKB1 1704/4885CA12 3913/4885 |
| US-20120128782-A1 | Multicomponent Degradable Cationic Polymers | PEF1, FIBP, PARN | ODC1 625/4885NFKB1 2868/4885CA12 4148/4885 |
| US-20180028455-A1 | PEPTIDE/PARTICLE DELIVERY SYSTEMS | VEGFA, IAPP, FLT1 | ODC1 4229/4885NFKB1 1494/4885CA12 3706/4885 |
| US-20140294909-A1 | NANOCOMPOSITES OF GOLD AND POLYMERS | HNRNPL, HNRNPLL, ACSL3 | ODC1 3530/4885NFKB1 4181/4885CA12 943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.