Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 3/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | BCL6 | P41182 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875479 | 0.89 | NAMPT (0.40) | NAMPTCHRNA7KCNH2DRD2DRD3 | |
| SCHEMBL874015 | 0.85 | DRD2 (0.41) | NAMPTBTKCHRNA7KCNH2DRD2 | |
| SCHEMBL873658 | 0.84 | NAMPT (0.39) | NAMPTCHRNA7KCNH2DRD2DRD3 | |
| SCHEMBL874516 | 0.82 | NAMPT (0.39) | NAMPTCHRNA7KCNH2RAB9AMAPT | |
| SCHEMBL874059 | 0.81 | NAMPT (0.41) | NAMPTCHRNA7DRD2DRD3RAB9A | |
| SCHEMBL873821 | 0.81 | NAMPT (0.39) | NAMPTBTKCHRNA7KCNH2RAB9A | |
| SCHEMBL875501 | 0.81 | CHRNA7 (0.40) | NAMPTBTKCHRNA7KCNH2MAPT | |
| SCHEMBL874083 | 0.76 | KDM4E (0.38) | NAMPTCHRNA7KCNH2RAB9AMAPT | |
| SCHEMBL874686 | 0.74 | CYP3A4 (0.42) | NAMPTCHRNA7KCNH2DRD2DRD3 | |
| SCHEMBL874571 | 0.74 | MAPT (0.38) | CHRNA7RAB9AMAPTNPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038905-A1 | THIENOPYRIDINE NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |