SCHEMBL8740212

SCHEMBL8740212

Cc1ccccc1C(C)(C)OO

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
ALOX15 P16050 1/20 0.52
GABRA1 P14867 1/20 0.43
GABRB2 P47870 1/20 0.43
TSHR P16473 2/20 0.39
ACHE P22303 2/20 0.39
TDP1 Q9NUW8 2/20 0.38
CASR P41180 1/20 0.38
CYP3A4 P08684 1/20 0.36
CA2 P00918 2/20 0.34
MAPK1 P28482 1/20 0.34
TRPA1 O75762 1/20 0.34
ATM Q13315 1/20 0.34
ESR1 P03372 2/20 0.32
CA1 P00915 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CHRM3 P20309 2/20 0.32
GAA P10253 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2808073 0.85 ALDH1A1 (0.61) ALDH1A1ALOX15GABRA1GABRB2TSHR
SCHEMBL28853148 0.83 TRPA1 (0.46) ALDH1A1ALOX15GABRA1GABRB2TSHR
SCHEMBL10593629 0.81 TSHR (0.43) ALDH1A1ALOX15GABRA1GABRB2TSHR
SCHEMBL9508330 0.79 TSHR (0.41) ALDH1A1ALOX15GABRA1GABRB2TSHR
SCHEMBL1421189 0.79 ALDH1A1 (0.54) ALDH1A1ALOX15GABRA1GABRB2TSHR
SCHEMBL9899516 0.77 ALDH1A1 (0.52) ALDH1A1ALOX15GABRA1GABRB2TSHR
SCHEMBL13408217 0.77 TSHR (0.39) ALDH1A1ALOX15GABRA1GABRB2TSHR
SCHEMBL17507508 0.77 ACHE (0.39) ALDH1A1ALOX15GABRA1GABRB2TSHR
SCHEMBL1318701 0.77 TSHR (0.39) ALDH1A1ALOX15GABRA1GABRB2TSHR
SCHEMBL7949339 0.77 GABRA1 (0.39) ALDH1A1ALOX15GABRA1GABRB2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105324374-A N-substituted acyl-imino-pyridine compounds and derivatives for combating animal pests BASF SE 2016-02-10 CN disclosed
US-5644004-A Multi-component ethylenically unsaturated peroxyesters ELF ATOCHEM NORTH AMERICA, INC. (US) 1997-07-01 US disclosed
US-5420173-A Curing unsaturated polyesters and peroxyester compositions ARKEMA INC. 1995-05-30 US disclosed