Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | CASR | P41180 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10775519 | 0.88 | MEN1 (0.51) | SIGMAR1POLBBCHENPC1RAB9A | |
| SCHEMBL27941499 | 0.80 | MTNR1A (0.47) | SIGMAR1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL19853394 | 0.80 | SIGMAR1 (0.57) | SIGMAR1CASRPOLBBCHEMEN1 | |
| SCHEMBL5487228 | 0.79 | KMT2A (0.47) | SIGMAR1CASRBCHEMEN1KMT2A | |
| SCHEMBL27704266 | 0.78 | SIGMAR1 (0.50) | SIGMAR1CASRPOLBBCHEMEN1 | |
| Anisole SCHEMBL946396 | 0.76 | CASR (0.62) | SIGMAR1CASRNPC1SMN1; SMN2KDM4E | |
| SCHEMBL3413593 | 0.74 | SIGMAR1 (0.65) | SIGMAR1CASRPOLBMEN1KMT2A | |
| SCHEMBL22899588 | 0.74 | SIGMAR1 (0.65) | SIGMAR1CASRPOLBMEN1KMT2A | |
| SCHEMBL143708 | 0.74 | SIGMAR1 (0.65) | SIGMAR1CASRPOLBMEN1KMT2A | |
| SCHEMBL11265712 | 0.74 | MTNR1A (0.54) | SIGMAR1CASRBCHENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624961-A | Benzylaminoethoxybenzene derivatives, production thereof and use thereof | JAPAN TOBACCO INC. (JP) | 1997-04-29 | — | — | US | claimed |
| EP-0693474-A1 | NOVEL BENZYLAMINOETHOXYBENZENE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Toyo Boseki Kabushiki Kaisha (JP) | 1996-01-24 | — | — | EP | claimed |
| CN-1114644-A | Novel benzylaminoethoxybenzene derivatives, production thereof and use thereof | TOYO BOSEKI (JP) | 1996-01-10 | — | — | CN | claimed |
| JP-7224013-A | — | — | None | — | — | JP | disclosed |
| US-5624961-A | Benzylaminoethoxybenzene derivatives, production thereof and use thereof | JAPAN TOBACCO INC. (JP) | 1997-04-29 | — | — | US | disclosed |
| US-5624961-A | Benzylaminoethoxybenzene derivatives, production thereof and use thereof | JAPAN TOBACCO INC. (JP) | 1997-04-29 | — | — | US | disclosed |
| US-5624961-A | Benzylaminoethoxybenzene derivatives, production thereof and use thereof | JAPAN TOBACCO INC. (JP) | 1997-04-29 | — | — | US | disclosed |
| EP-0693474-A4 | NOVEL BENZYLAMINOETHOXYBENZENE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | TOYO BOSEKI (JP) | 1997-02-05 | — | — | EP | disclosed |
| EP-0693474-A1 | NOVEL BENZYLAMINOETHOXYBENZENE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Toyo Boseki Kabushiki Kaisha (JP) | 1996-01-24 | — | — | EP | disclosed |
| EP-0693474-A1 | NOVEL BENZYLAMINOETHOXYBENZENE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Toyo Boseki Kabushiki Kaisha (JP) | 1996-01-24 | — | — | EP | disclosed |
| CN-1114644-A | Novel benzylaminoethoxybenzene derivatives, production thereof and use thereof | TOYO BOSEKI (JP) | 1996-01-10 | — | — | CN | disclosed |
| CN-1114644-A | Novel benzylaminoethoxybenzene derivatives, production thereof and use thereof | TOYO BOSEKI (JP) | 1996-01-10 | — | — | CN | disclosed |
| CN-1114644-A | Novel benzylaminoethoxybenzene derivatives, production thereof and use thereof | TOYO BOSEKI (JP) | 1996-01-10 | — | — | CN | disclosed |
| JP-H07224013-A | NEW BENZYLAINOETHOXYBNENZENE DERIVARTIVE | TOYOBO CO LTD | 1995-08-22 | — | — | JP | disclosed |
| WO-1995021811-A1 | NOVEL BENZYLAMINOETHOXYBENZENE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1995-08-17 | — | — | WO | disclosed |