SCHEMBL5553018

SCHEMBL5553018

CCc1ccccc1OC(N)=S.NC(O)=S

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.43
MAPT P10636 3/20 0.43
NPSR1 Q6W5P4 1/20 0.43
ALDH1A1 P00352 1/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.38
ATM Q13315 1/20 0.38
KDM4E B2RXH2 1/20 0.38
TSHR P16473 1/20 0.37
THRA P10827 1/20 0.37
THRB P10828 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
LMNA P02545 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9124756 0.98 L3MBTL1 (0.42) L3MBTL1MAPTNPSR1ALDH1A1GAA
SCHEMBL2130141 0.98 L3MBTL1 (0.42) L3MBTL1MAPTNPSR1ALDH1A1GAA
SCHEMBL15173321 0.96 L3MBTL1 (0.46) L3MBTL1MAPTNPSR1ALDH1A1GAA
SCHEMBL27432911 0.95 L3MBTL1 (0.44) L3MBTL1MAPTNPSR1ALDH1A1GAA
SCHEMBL28774067 0.90 MAPT (0.41) L3MBTL1MAPTNPSR1ALDH1A1GAA
SCHEMBL9868958 0.85 GABRA1 (0.37) L3MBTL1MAPTNPSR1ALDH1A1GAA
SCHEMBL4397092 0.83 THRA (0.49) MAPTKDM4ETHRATHRBMEN1
SCHEMBL2127453 0.82 THRA (0.48) MAPTKDM4ETHRATHRBMEN1
SCHEMBL28419901 0.82 THRA (0.43) THRATHRBLMNASMN1; SMN2
SCHEMBL9650772 0.81 THRA (0.57) MAPTTSHRTHRATHRBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107828085-B A kind of naphthenic base heavy traffic paving asphalt modified stabilizer 东营润丰博越石油技术有限公司 2019-06-14 CN claimed
CN-109423274-A A kind of preparation method of nano-crystal with core-shell structure body 苏州星烁纳米科技有限公司 2019-03-05 CN claimed
CN-108997700-A Low temperature resistant elastomer resin material and preparation method thereof suitable for polar region extremely cold area 福建省二轻工业研究所 2018-12-14 CN claimed
CN-105037865-B A kind of modified waste rubber powder and preparation method and application 华南理工大学 2017-10-20 CN claimed
CN-106281585-A A kind of multifunctional additive for lubricating oil 梁方英 2017-01-04 CN claimed
CN-106084391-A A kind of municipal administration road and bridge safeguard asphalt modification inorganic agent 王璐 2016-11-09 CN claimed
CN-115746472-B PVC composite heat stabilizer containing dibenzoylmethane 安徽佳先功能助剂股份有限公司 2023-10-20 CN disclosed
US-20230257488-A1 REACTIVE CARBONATE FOR ELASTOMERIC ARTICLES IMERYS USA INC (US) 2023-08-17 US disclosed
US-11667732-B2 Reactive carbonate for elastomeric articles IMERYS USA, INC. (US) 2023-06-06 US disclosed
CN-112135732-B Laminate and tube 大金工业株式会社 2023-06-02 CN disclosed
CN-113454153-B In-line ultrasonic inspection for detecting partial vulcanization of rubber mixtures in-situ silylation of light-colored fillers 朗盛德国有限责任公司 2023-04-28 CN disclosed
US-11453250-B2 Pneumatic tire for passenger vehicle THE YOKOHAMA RUBBER CO., LTD. (JP) 2022-09-27 US disclosed
CN-110481118-A A kind of furane resins Compound Modification Asphalt Waterproof Materials and preparation method thereof WUHU TANGHUA BUILDING MATERIAL TECH CO LTD 2019-11-22 CN disclosed
CN-102358070-B Laminated body and method of producing same as well as innerliner for pneumatic tire and pneumatic tire BRIDGESTONE CORP 2014-05-07 CN disclosed
CN-102596539-A Cross-linking agent batch containing marking substances, novel cross-linkable rubber mixtures, method for the production thereof and use thereof RHEIN CHEMIE RHEINAU GMBH 2012-07-18 CN disclosed
CN-100402395-C Paper-feeding roller SUMITOMO RUBBER IND (JP) 2008-07-16 CN disclosed
EP-1840399-A1 COLLAPSIBLE COLUMN NSK Ltd., (JP) 2007-10-03 EP disclosed
CN-1760100-A Paper-feeding roller SUMITOMO RUBBER IND (JP) 2006-04-19 CN disclosed
CN-1272509-A Polyurethane rubber composite containing modified rubber gel LEYIN CHEMICAL LEYINNO GMBH (DE) 2000-11-08 CN disclosed
US-5252391-A Surface treated sliding or rolling contact element and rolling bearing NIPPON SEIKO KABUSHIKI KAISHA (JP) 1993-10-12 US disclosed