Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ACHE | P22303 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.37 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14142398 | 0.80 | ACHE (0.76) | KDM4EACHEALDH1A1GLAGAA | |
| SCHEMBL9035866 | 0.78 | KDM4E (0.47) | KDM4EACHEALDH1A1GLAGAA | |
| SCHEMBL9458166 | 0.78 | KDM4E (0.53) | KDM4EACHEALDH1A1GLAGAA | |
| SCHEMBL7359720 | 0.76 | KDM4E (0.62) | KDM4EACHEALDH1A1GLAGAA | |
| SCHEMBL5952593 | 0.72 | CTRC (0.38) | ACHE | |
| SCHEMBL31321876 | 0.71 | KDM4E (1.00) | KDM4EACHEALDH1A1GLAGAA | |
| SCHEMBL9036025 | 0.71 | KDM4E (1.00) | KDM4EACHEALDH1A1GLAGAA | |
| SCHEMBL23023380 | 0.69 | KDM4E (0.81) | KDM4EACHEALDH1A1GLAGAA | |
| SCHEMBL1582991 | 0.69 | METAP1 (0.43) | ACHECYP19A1 | |
| SCHEMBL9457818 | 0.69 | KDM4E (0.81) | KDM4EACHEALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0769940-A4 | — | — | 1997-06-11 | — | — | EP | disclosed |
| EP-0769940-A1 | INDENE sPLA 2? INHIBITORS | ELI LILLY AND COMPANY (US) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996003120-A1 | INDENE sPLA2 INHIBITORS | ELI LILLY AND COMPANY (US) | 1996-02-08 | — | — | WO | disclosed |