Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | EIF4A1 | P60842 | 7/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874685 | 0.82 | RAB9A (0.46) | RAB9APTPN11CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL14015121 | 0.80 | KDM4E (0.53) | RAB9AEIF4A1MEN1KMT2AGAA | |
| SCHEMBL8867718 | 0.78 | RAB9A (1.00) | RAB9ACSNK2A2CSNK2BCSNK2A1MEN1 | |
| SCHEMBL874282 | 0.78 | SMN1; SMN2 (0.47) | RAB9APTPN11MEN1KMT2AGAA | |
| SCHEMBL874463 | 0.77 | RAB9A (0.65) | RAB9APTPN11CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL874528 | 0.77 | RAB9A (0.72) | RAB9ACSNK2A2CSNK2BCSNK2A1MEN1 | |
| SCHEMBL874739 | 0.76 | RAB9A (0.71) | RAB9APTPN11CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL17978505 | 0.73 | MGAM (0.56) | RAB9ACSNK2A2CSNK2BCSNK2A1MEN1 | |
| SCHEMBL11155880 | 0.71 | EIF4A1 (0.61) | RAB9AEIF4A1MEN1KMT2AGAA | |
| SCHEMBL2823686 | 0.71 | RAB9A (0.70) | RAB9APTPN11MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038905-A1 | THIENOPYRIDINE NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |