Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874805 | 0.86 | MAPT (0.43) | RAB9APPARAALDH1A1MAPTKMT2A | |
| SCHEMBL874282 | 0.83 | SMN1; SMN2 (0.47) | RAB9APPARAPTPN11ALDH1A1MAPT | |
| SCHEMBL874100 | 0.82 | RAB9A (0.64) | RAB9APPARAPTPN11ALDH1A1MAPT | |
| SCHEMBL875702 | 0.74 | NAMPT (0.44) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL12517440 | 0.69 | MEN1 (0.74) | RAB9AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL874409 | 0.68 | CD274 (0.55) | ALDH1A1MAPTKMT2ACYP1A2TP53 | |
| SCHEMBL17374873 | 0.68 | RAB9A (0.55) | RAB9APPARAPTPN11ALDH1A1MAPT | |
| SCHEMBL1553829 | 0.68 | MAPT (0.56) | PPARAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2823686 | 0.66 | RAB9A (0.70) | RAB9APPARAPTPN11ALDH1A1MAPT | |
| SCHEMBL17978505 | 0.66 | MGAM (0.56) | RAB9AMAPTCSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |