SCHEMBL8741347

SCHEMBL8741347

O=C(O)c1cccc(Oc2ccccc2S(=O)(=O)c2ccccc2Oc2cccc(C(=O)O)c2)c1

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ AKR1C3 P42330 1/20 0.63
▸ MRGPRX4 Q96LA9 1/20 0.54
▸ KMO O15229 1/20 0.50
▸ TTR P02766 2/20 0.49
▸ PPARG P37231 1/20 0.48
▸ NR4A2 P43354 2/20 0.48
▸ NPC1 O15118 1/20 0.47
▸ POLB P06746 1/20 0.47
▸ CYP2C9 P11712 1/20 0.47
▸ RAB9A P51151 1/20 0.47
▸ KDM4E B2RXH2 1/20 0.47
▸ GCK P35557 1/20 0.46
▸ HDAC8 Q9BY41 1/20 0.45
▸ F10 P00742 1/20 0.45
▸ CASP1 P29466 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ KAT6A Q92794 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29466776 0.85 AKR1C3 (0.79) AKR1C3MRGPRX4KMOTTRNR4A2
SCHEMBL1042630 0.85 AKR1C3 (0.79) AKR1C3MRGPRX4KMOTTRNR4A2
Hydrochloric Acid SCHEMBL8434547 0.84 AKR1C3 (0.76) AKR1C3MRGPRX4KMOTTRPPARG
Hydrochloric Acid SCHEMBL8434544 0.84 AKR1C3 (0.76) AKR1C3MRGPRX4KMOTTRPPARG
SCHEMBL10963567 0.83 CASP1 (0.56) TTRNPC1POLBRAB9ACASP1
SCHEMBL27145020 0.81 ALPL (0.44) POLBGCKCASP1ALDH1A1KMT2A
SCHEMBL146565 0.80 CASP1 (0.50) CASP1KMT2A
SCHEMBL502864 0.80 CASP1 (0.50) CASP1KMT2A
SCHEMBL27818369 0.80 AKR1C3 (0.69) AKR1C3MRGPRX4KMOTTRNR4A2
SCHEMBL921873 0.80 AKR1C3 (0.69) AKR1C3MRGPRX4KMOTTRNR4A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113527101-B Novel compound, polymer, process for producing the same, photosensitive resin composition, pattern forming process, cured film, and electronic component 信越化学工业株式会社 2024-04-23 — — CN disclosed
EP-3896114-B1 POLYIMIDE RESIN AND METHOD OF PRODUCING THE SAME, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD AND METHOD OF FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT SHINETSU CHEMICAL CO (JP) 2023-10-18 — — EP disclosed
US-11572442-B2 Compound, polyimide resin and method of producing the same, photosensitive resin composition, patterning method and method of forming cured film, interlayer insulating film, surface protective film, and electronic component INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2023-02-07 — — US disclosed
CN-113527101-A Novel compound, polymer and method for producing same, photosensitive resin composition, method for forming pattern, cured film, and electronic component 信越化学工业株式会社 2021-10-22 — — CN disclosed
EP-3896114-A1 NOVEL COMPOUND, POLYIMIDE RESIN AND METHOD OF PRODUCING THE SAME, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD AND METHOD OF FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT Shin-Etsu Chemical Co., Ltd. (JP) 2021-10-20 — — EP disclosed
US-20210317270-A1 NOVEL COMPOUND, POLYIMIDE RESIN AND METHOD OF PRODUCING THE SAME, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD AND METHOD OF FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-10-14 — — US disclosed
US-5594089-A TOUGH THERMOPLASTIC FOR AEROSPACE APPLICATIONS, POLYAMIDE WITH IMIDE ENDCAPPING THE BOEING COMPANY 1997-01-14 — — US disclosed
US-5198526-A Heterocycle oligomers with multidimensional morphology THE BOEING COMPANY (US) 1993-03-30 — — US disclosed
US-5126410-A Solvent resistant polybenzoxazoles, polybenzothiazoles and polybenzimidazoles THE BOEING COMPANY (US) 1992-06-30 — — US disclosed
US-5120819-A Heat and sovent-resistant polybenzoxazoles,-thiazoles and -imidazoles for aerospace applications BOEING COMPANY (US) 1992-06-09 — — US disclosed
US-5082905-A Blended heterocycles THE BOEING COMPANY (US) 1992-01-21 — — US disclosed
US-5066541-A Heterocycle oligomer blends THE BOEING COMPANY (US) 1991-11-19 — — US disclosed
US-4965336-A PHENYLIMIDE ACID HALIDE ENCAPPED POLYBENZOXAZLES; CURABLE, SOLVENT RESISTANCE PREPREGS THE BOEING COMPANY (US) 1990-10-23 — — US disclosed
US-4868270-A Heterocycle sulfone oligomers and blends THE BOEING COMPANY (US) 1989-09-19 — — US disclosed
EP-0311735-A2 Heterocycle sulfone oligomers and blends The Boeing Company (US) 1989-04-19 — — EP disclosed
EP-0309649-A2 High performance heterocycle oligomers and blends THE BOEING COMPANY (US) 1989-04-05 — — EP disclosed
US-4547553-A CROSSLINKED SOLVENT RESISTANT THERMOPLASTIC RESIN THE BOEING COMPANY (US) 1985-10-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11572442-B2 Compound, polyimide resin and method of producing the same, photosensitive resin composition, patterning method and method of forming cured film, interlayer insulating film, surface protective film, and electronic component BRIX1, RBX1, HAX1 AKR1C3 3444/4885MRGPRX4 263/4885KMO 3211/4885
US-20210317270-A1 NOVEL COMPOUND, POLYIMIDE RESIN AND METHOD OF PRODUCING THE SAME, PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING METHOD AND METHOD OF FORMING CURED FILM, INTERLAYER INSULATING FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT BRIX1, HAX1, RBX1 AKR1C3 3251/4885MRGPRX4 236/4885KMO 3307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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