Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 14/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873796 | 0.91 | GPR139 (0.48) | GPR139HPGDNPSR1KMT2AALDH1A1 | |
| SCHEMBL876799 | 0.89 | GPR139 (0.51) | GPR139NPSR1ALDH1A1 | |
| SCHEMBL874810 | 0.87 | GPR139 (0.52) | GPR139HPGDTSHRNPSR1KMT2A | |
| SCHEMBL878345 | 0.85 | GPR139 (0.52) | GPR139HPGDTSHRNPSR1KMT2A | |
| SCHEMBL876684 | 0.85 | GPR139 (0.52) | GPR139HPGDTSHRNPSR1KMT2A | |
| SCHEMBL877706 | 0.84 | MMP2 (0.45) | GPR139HPGDNPSR1KMT2AALDH1A1 | |
| SCHEMBL877880 | 0.84 | GPR139 (0.44) | GPR139HPGDNPSR1KMT2AALDH1A1 | |
| SCHEMBL877229 | 0.83 | GPR139 (0.51) | GPR139NPSR1ALDH1A1 | |
| SCHEMBL875064 | 0.82 | GPR139 (0.49) | GPR139HPGDTSHRNPSR1KMT2A | |
| SCHEMBL877287 | 0.81 | MMP1 (0.47) | GPR139HPGDTSHRNPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | claimed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | claimed |
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |