Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5868210 | 0.81 | PTGS2 (0.41) | HTTTDP1GAAKMT2ATSHR | |
| SCHEMBL8892649 | 0.79 | HTT (0.40) | HTTTDP1GAAKMT2ATSHR | |
| SCHEMBL2152622 | 0.78 | TSHR (0.41) | HTTTDP1GAAKMT2ATSHR | |
| SCHEMBL8727671 | 0.78 | TSHR (0.41) | HTTTDP1GAAKMT2ATSHR | |
| SCHEMBL11413990 | 0.78 | CA2 (0.50) | HTTTDP1GAAKMT2ATSHR | |
| SCHEMBL6152627 | 0.77 | ALDH1A1 (0.53) | HTTTDP1GAAKMT2ATSHR | |
| SCHEMBL9320332 | 0.77 | CA1 (0.53) | HTTTDP1GAAKMT2ATSHR | |
| SCHEMBL9320358 | 0.75 | VCAM1 (0.47) | HTTGAAKMT2ALMNAALDH1A1 | |
| SCHEMBL29029427 | 0.74 | CA12 (0.36) | CA2CA12CA1CA9 | |
| SCHEMBL2685223 | 0.73 | HTT (0.47) | HTTTDP1KMT2ATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0464736-B1 | A process for producing 5-amino-4-halogeno-1H-pyrazole compounds | FUJI PHOTO FILM CO LTD (JP) | 1997-01-02 | — | — | EP | claimed |
| US-5122612-A | PROCESS FOR PRODUCING 5-AMINO-4-HALOGENO-1H-PYRAZOLE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1992-06-16 | — | — | US | claimed |
| EP-0464736-A1 | A process for producing 5-amino-4-halogeno-1H-pyrazole compounds | Fuji Photo Film Co., Ltd. (JP) | 1992-01-08 | — | — | EP | claimed |
| EP-0464736-B1 | A process for producing 5-amino-4-halogeno-1H-pyrazole compounds | FUJI PHOTO FILM CO LTD (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5122612-A | PROCESS FOR PRODUCING 5-AMINO-4-HALOGENO-1H-PYRAZOLE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1992-06-16 | — | — | US | disclosed |
| EP-0464736-A1 | A process for producing 5-amino-4-halogeno-1H-pyrazole compounds | Fuji Photo Film Co., Ltd. (JP) | 1992-01-08 | — | — | EP | disclosed |