Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | S100A4 | P26447 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PDE2A | O00408 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9320125 | 0.84 | ALDH1A1 (0.45) | KMT2AGAAESPL1LMNAALDH1A1 | |
| SCHEMBL5868210 | 0.83 | PTGS2 (0.41) | HTTCYP1A2KMT2AGAATSHR | |
| SCHEMBL9320358 | 0.83 | VCAM1 (0.47) | HTTKMT2AGAALMNAS1PR4 | |
| SCHEMBL9320217 | 0.81 | CYP1A2 (0.40) | HTTCYP1A2POLBKMT2ALMNA | |
| SCHEMBL9320484 | 0.81 | KMT2A (0.35) | HTTCYP1A2POLBKMT2AGAA | |
| SCHEMBL11413990 | 0.79 | CA2 (0.50) | HTTKMT2AGAATSHRLMNA | |
| SCHEMBL2152622 | 0.79 | TSHR (0.41) | HTTKMT2AGAATSHRLMNA | |
| SCHEMBL8727671 | 0.79 | TSHR (0.41) | HTTKMT2AGAATSHRLMNA | |
| SCHEMBL9320332 | 0.79 | CA1 (0.53) | HTTCYP1A2KMT2AGAATSHR | |
| SCHEMBL8742964 | 0.79 | HTT (0.39) | HTTPOLBKMT2AGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633355-A | DISPERSE DYES | SANDOZ LTD. (CH) | 1997-05-27 | — | — | US | claimed |
| US-5633355-A | DISPERSE DYES | SANDOZ LTD. (CH) | 1997-05-27 | — | — | US | disclosed |