Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.45 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.40 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4341361 | 0.80 | CA2 (0.43) | CA2CA12CA1CA9CHKA | |
| SCHEMBL8103057 | 0.80 | CHRNB2 (0.54) | CA2CA12CA1CA9CHKA | |
| SCHEMBL3635077 | 0.77 | — | — | |
| SCHEMBL316937 | 0.76 | CHRNB2 (0.50) | CA2CA12CA1CA9CHKA | |
| SCHEMBL20369074 | 0.76 | CA2 (0.48) | CA2CA12CA1CA9CHKA | |
| SCHEMBL6721 | 0.76 | CHRNB2 (0.50) | CA2CA12CA1CA9CHKA | |
| SCHEMBL1780077 | 0.76 | LMNA (0.43) | CA2CA12CA1CA9CHKA | |
| SCHEMBL304390 | 0.75 | ALDH1A1 (0.50) | CA2CHKAHSD11B1POLBHPGD | |
| Ethane SCHEMBL27604108 | 0.74 | CHRNB2 (0.48) | CA2CA12CA1CA9CHKA | |
| SCHEMBL28744445 | 0.74 | CHRNB2 (0.48) | CA2CA12CA1CA9CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5354913-A | Chemical intermediates for drugs or drugs as thromboxane, prostaglandin antagonist, lipoxygenase enzyme inhibitor, antioxidants | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-11 | — | — | US | claimed |
| EP-0751113-A1 | Optically active phenol derivatives and preparation thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-02 | — | — | EP | disclosed |
| EP-0537954-B1 | Process of preparing diphenylmethane derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1996-07-24 | — | — | EP | disclosed |
| US-5420363-A | Catalytic reaction of phenol with secondary carbinol for enantiomorphs | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-05-30 | — | — | US | disclosed |
| US-5354913-A | Chemical intermediates for drugs or drugs as thromboxane, prostaglandin antagonist, lipoxygenase enzyme inhibitor, antioxidants | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-11 | — | — | US | disclosed |
| EP-0582382-A2 | Optically active phenol derivatives and preparation thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-02-09 | — | — | EP | disclosed |
| EP-0295037-B1 | PHENOL DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-08-18 | — | — | EP | disclosed |
| US-5235091-A | Reacting a phenol compound with a stilbene compound in presence of methanesulfonic acid | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0537954-A1 | Process of preparing diphenylmethane derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-04-21 | — | — | EP | disclosed |
| US-5162571-A | Phenol derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-11-10 | — | — | US | disclosed |
| EP-0295037-A2 | Phenol derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1988-12-14 | — | — | EP | disclosed |