Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.45 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL316937 | 1.00 | CHRNB2 (0.50) | CHRNB2CHRNA4CHRNA3CHRNB4CA2 | |
| Ethane SCHEMBL27604108 | 0.98 | CHRNB2 (0.48) | CHRNB2CHRNA4CHRNA3CHRNB4CA2 | |
| Hydrochloric Acid SCHEMBL399052 | 0.98 | CHRNB2 (0.48) | CHRNB2CHRNA4CHRNA3CHRNB4CA2 | |
| SCHEMBL18689130 | 0.92 | CA2 (0.50) | CHRNB2CHRNA4CHRNA3CHRNB4CA2 | |
| Hydrochloric Acid SCHEMBL23778305 | 0.90 | CA2 (0.48) | CHRNB2CHRNA4CHRNA3CHRNB4CA2 | |
| Phosphoric Acid SCHEMBL29151557 | 0.90 | CHRNB2 (0.43) | CHRNB2CHRNA4CHRNA3CHRNB4CA2 | |
| SCHEMBL13935798 | 0.88 | CA2 (0.47) | CHRNB2CHRNA4CHRNA3CHRNB4CA2 | |
| Fumaric Acid SCHEMBL27690913 | 0.88 | HCAR2 (0.42) | CHRNB2CHRNA4CHRNA3CHRNB4CA2 | |
| SCHEMBL4919297 | 0.86 | — | — | |
| SCHEMBL16474061 | 0.85 | CA2 (0.47) | CHRNB2CHRNA4CHRNA3CHRNB4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1021 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119793223-A | Nanofiltration membrane, preparation method thereof and filtering device | 清华大学 | 2025-04-11 | — | — | CN | claimed |
| US-12264133-B2 | Compounds, compositions and methods | CYTOKINETICS, INCORPORATED (US) | 2025-04-01 | — | — | US | claimed |
| CN-118085005-A | 18 Beta-glycyrrhetinic acid derivative and preparation method and application thereof | 石河子大学 | 2024-05-28 | — | — | CN | claimed |
| CN-111819176-B | 4-azaindole compounds | 百时美施贵宝公司 | 2023-12-15 | — | — | CN | claimed |
| CN-110799503-B | Synthesis of Meicartine | 美国安进公司 | 2023-06-27 | — | — | CN | claimed |
| CN-115605480-A | Sulfonamidine substituted compounds and their use as beta-lactamase inhibitors | 宁夏农林科学院（CN） | 2023-01-13 | — | — | CN | claimed |
| US-20230010299-A1 | HETEROCYCLIC TRPML1 AGONISTS | LIBRA THERAPEUTICS, INC. | 2023-01-12 | — | — | US | claimed |
| EP-4058145-A1 | HETEROCYCLIC TRPML1 AGONISTS | Libra Therapeutics, Inc. (US) | 2022-09-21 | — | — | EP | claimed |
| CN-114644838-A | Method for preparing black phosphorus-piperazine compound composite material | 山东玥能新材料科技有限公司 | 2022-06-21 | — | — | CN | claimed |
| US-20220185779-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INCORPORATED | 2022-06-16 | — | — | US | claimed |
| EP-0765865-A1 | 2-ACYLAMINOPROPANOL COMPOUND AND MEDICINAL COMPOSITION | SEIKAGAKU CORPORATION (JP) | 1997-04-02 | — | — | EP | claimed |
| US-5354913-A | Chemical intermediates for drugs or drugs as thromboxane, prostaglandin antagonist, lipoxygenase enzyme inhibitor, antioxidants | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-11 | — | — | US | claimed |
| US-5262534-A | Process for the preparation of nonaromatic cyclic nitrogen-containing compounds | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-11-16 | — | — | US | claimed |
| US-5245032-A | CATALYTIC PROCESSES FOR THE PREPARATION OF N,N,N-TRISUBSTITUTED NITROGEN-CONTAINING COMPOUNDS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-09-14 | — | — | US | claimed |
| US-5191104-A | Complex catalysts | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-03-02 | — | — | US | claimed |
| EP-0478074-A2 | Alkoxylation of carboxylated compounds | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) | 1992-04-01 | — | — | EP | claimed |
| EP-0476783-A1 | Processes for the preparation of nonaromatic N,N,N-trisubstituted nitrogen-containing compounds | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) | 1992-03-25 | — | — | EP | claimed |
| EP-0476782-A1 | Catalytic processes for the preparation of N,N,N-trisubstituted nitrogen-containing compounds | UNION CARBIDE CHEMICALS AND PLASTICS COMPANY, INC. (US) | 1992-03-25 | — | — | EP | claimed |
| EP-0020303-B1 | GUANIDINES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL PREPARATIONS CONTAINING SUCH COMPOUNDS AND THEIR APPLICATION | CIBA-GEIGY AG (CH) | 1985-08-28 | — | — | EP | claimed |
| EP-0020303-A1 | Guanidines, process for their preparation, pharmaceutical preparations containing such compounds and their application | CIBA-GEIGY AG (CH) | 1980-12-10 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220185779-A1 | COMPOUNDS, COMPOSITIONS AND METHODS | TNNI3, TNNC1, TNNT2 | CHRNB2 1261/4885CHRNA4 2464/4885CHRNA3 1841/4885 |
| US-12264133-B2 | Compounds, compositions and methods | TNNI3, TNNC1, TNNT2 | CHRNB2 1261/4885CHRNA4 2464/4885CHRNA3 1841/4885 |
| US-20230010299-A1 | HETEROCYCLIC TRPML1 AGONISTS | TRPM7, TRPM2, TRPM5 | CHRNB2 534/4885CHRNA4 572/4885CHRNA3 487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.