Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290478 | 0.84 | ALDH1A1 (0.37) | ALDH1A1HSD17B10LMNAPOLBMEN1 | |
| SCHEMBL8971069 | 0.82 | ALDH1A1 (0.36) | ALDH1A1HSD17B10LMNAPOLBMEN1 | |
| SCHEMBL28422244 | 0.78 | ALDH1A1 (0.39) | ALDH1A1HSD17B10LMNAMEN1KMT2A | |
| SCHEMBL65116 | 0.78 | ALDH1A1 (0.39) | ALDH1A1HSD17B10LMNAKMT2AALOX15 | |
| SCHEMBL9218455 | 0.77 | ALDH1A1 (0.34) | ALDH1A1HSD17B10LMNAPOLBMEN1 | |
| SCHEMBL1444159 | 0.76 | ALDH1A1 (0.50) | ALDH1A1HSD17B10LMNAMEN1KMT2A | |
| SCHEMBL9218462 | 0.73 | ALDH1A1 (0.34) | ALDH1A1HSD17B10LMNAPOLBMEN1 | |
| SCHEMBL28694430 | 0.73 | ALDH1A1 (0.42) | ALDH1A1HSD17B10LMNAMEN1KMT2A | |
| SCHEMBL64224 | 0.70 | ALDH1A1 (0.32) | ALDH1A1HSD17B10LMNAALOX15MGAM | |
| SCHEMBL1444162 | 0.70 | ALDH1A1 (0.50) | ALDH1A1HSD17B10LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038905-A1 | THIENOPYRIDINE NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |