Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.54 |
| ▸ | CTSK | P43235 | 10/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744692 | 0.83 | CYP2A6 (0.43) | CTSSCTSKNISCHNOTUM | |
| SCHEMBL8744753 | 0.80 | CTSS (0.49) | CTSSCTSKLRRK2IDO1 | |
| SCHEMBL7432291 | 0.77 | ADORA2A (0.41) | CTSKLRRK2CHUK | |
| SCHEMBL8744764 | 0.77 | CTSS (0.48) | CTSSCTSKIDO1 | |
| SCHEMBL8744690 | 0.77 | KDM4E (0.49) | CTSSCTSKLRRK2IDO1 | |
| SCHEMBL8744832 | 0.74 | MCL1 (0.42) | CHUK | |
| SCHEMBL8744699 | 0.73 | CTSS (0.61) | CTSSCTSKIDO1 | |
| SCHEMBL3623102 | 0.73 | IDO1 (0.59) | CTSSCTSKLRRK2IDO1NISCH | |
| SCHEMBL18617328 | 0.72 | IDO1 (0.54) | CTSSCTSKLRRK2IDO1NISCH | |
| SCHEMBL13040762 | 0.70 | IDO1 (0.51) | CTSSCTSKLRRK2IDO1NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653421-B1 | Process for preparing 2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA (JP) | 1997-01-15 | — | — | EP | disclosed |
| US-5552557-A | Process for preparing 2-cyanoimidazole compounds by reaction of an amino ketone compound | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1996-09-03 | — | — | US | disclosed |
| EP-0653421-A1 | Process for preparing 2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |