Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432291 | 0.96 | ADORA2A (0.41) | MCL1ADORA1CYP11B1CYP11B2KDM4E | |
| SCHEMBL8744743 | 0.82 | MCL1 (0.41) | MCL1ADORA1KDM4EHPGDALDH1A1 | |
| SCHEMBL8744742 | 0.82 | CYP11B1 (0.43) | ADORA1CYP11B1CYP11B2KDM4EHPGD | |
| SCHEMBL8744752 | 0.82 | ERBB2 (0.41) | ADORA1KDM4EALDH1A1ADORA2AMEN1 | |
| SCHEMBL8744693 | 0.80 | CCNC (0.47) | ADORA1ADORA2AMAPK1GSK3BRAB9A | |
| SCHEMBL8744764 | 0.78 | CTSS (0.48) | ADORA1KDM4EHPGDALDH1A1ADORA2A | |
| SCHEMBL8744687 | 0.78 | KIF11 (0.47) | MYC | |
| SCHEMBL8744692 | 0.78 | CYP2A6 (0.43) | KDM4EHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL8744690 | 0.78 | KDM4E (0.49) | ADORA1KDM4EALDH1A1ADORA2AGAA | |
| SCHEMBL8744753 | 0.78 | CTSS (0.49) | ADORA1KDM4EHPGDL3MBTL1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653421-B1 | Process for preparing 2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA (JP) | 1997-01-15 | — | — | EP | disclosed |
| US-5552557-A | Process for preparing 2-cyanoimidazole compounds by reaction of an amino ketone compound | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1996-09-03 | — | — | US | disclosed |
| EP-0653421-A1 | Process for preparing 2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |