Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HK1 | P19367 | 1/20 | 0.44 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744752 | 0.81 | ERBB2 (0.41) | METAP2ALDH1A1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7432291 | 0.81 | ADORA2A (0.41) | CTSKALDH1A1RAB9AHPGDMAPT | |
| SCHEMBL8744690 | 0.81 | KDM4E (0.49) | CTSSCTSKIDO1ALDH1A1KDM4E | |
| SCHEMBL8744753 | 0.81 | CTSS (0.49) | CTSSCTSKIDO1METAP2RAB9A | |
| SCHEMBL8744832 | 0.78 | MCL1 (0.42) | ALDH1A1RAB9AHPGDMAPTKDM4E | |
| SCHEMBL8744699 | 0.77 | CTSS (0.61) | CTSSCTSKIDO1ALDH1A1KDM4E | |
| SCHEMBL8744714 | 0.77 | CTSS (0.54) | CTSSCTSKIDO1 | |
| SCHEMBL1399849 | 0.75 | ALDH1A1 (0.56) | IDO1METAP2ALDH1A1RAB9AHPGD | |
| SCHEMBL15676687 | 0.75 | IDO1 (0.49) | CTSSCTSKIDO1METAP2ALDH1A1 | |
| SCHEMBL7141828 | 0.73 | SMN1; SMN2 (0.55) | IDO1METAP2ALDH1A1RAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653421-B1 | Process for preparing 2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA (JP) | 1997-01-15 | — | — | EP | disclosed |
| US-5552557-A | Process for preparing 2-cyanoimidazole compounds by reaction of an amino ketone compound | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1996-09-03 | — | — | US | disclosed |
| EP-0653421-A1 | Process for preparing 2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |