Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | USP8 | P40818 | 2/20 | 0.40 |
| ▸ | USP7 | Q93009 | 2/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25357822 | 0.85 | USP8 (0.38) | KDM4EMAPTTDP1HSP90AA1HSP90AB1 | |
| SCHEMBL8744696 | 0.81 | L3MBTL1 (0.46) | KDM4EMAPTTDP1HSP90AA1HSP90AB1 | |
| SCHEMBL7144947 | 0.77 | HSP90AA1 (0.47) | MAPTHSP90AA1HSP90AB1LMNAMEN1 | |
| SCHEMBL8744743 | 0.77 | MCL1 (0.41) | KDM4EMAPTTDP1HSP90AA1PSMB8 | |
| SCHEMBL8744690 | 0.76 | KDM4E (0.49) | KDM4EPSMB8GAA | |
| SCHEMBL1676535 | 0.76 | HSP90AA1 (0.54) | KDM4EMAPTHSP90AA1HSP90AB1LMNA | |
| SCHEMBL7674674 | 0.76 | HSP90AA1 (0.51) | KDM4EMAPTTDP1HSP90AA1HSP90AB1 | |
| SCHEMBL28573837 | 0.73 | SMN1; SMN2 (0.44) | KDM4EMAPTHSP90AA1HSP90AB1LMNA | |
| SCHEMBL27592593 | 0.73 | PTPN1 (0.46) | KDM4EMAPTTDP1HSP90AA1HSP90AB1 | |
| SCHEMBL8744731 | 0.72 | HSP90AB1 (0.45) | KDM4EMAPTTDP1HSP90AB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653421-B1 | Process for preparing 2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA (JP) | 1997-01-15 | — | — | EP | disclosed |
| US-5552557-A | Process for preparing 2-cyanoimidazole compounds by reaction of an amino ketone compound | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1996-09-03 | — | — | US | disclosed |
| EP-0653421-A1 | Process for preparing 2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |
| US-5045557-A | Imidazable fungicides and use thereof | SCHERING AGROCHEMICALS LTD. (GB) | 1991-09-03 | — | — | US | disclosed |
| EP-0284277-A1 | Cyanoimidazole fungicides | AgrEvo UK Limited (GB) | 1988-09-28 | — | — | EP | disclosed |