Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | USP8 | P40818 | 1/20 | 0.37 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25357822 | 0.85 | USP8 (0.38) | HSP90AB1MAPTKDM4EMEN1NPC1 | |
| SCHEMBL8744776 | 0.81 | LRRK2 (0.43) | MAPTKDM4EMEN1NPC1KMT2A | |
| SCHEMBL8744742 | 0.77 | CYP11B1 (0.43) | MAPTKDM4EMEN1NPC1KMT2A | |
| SCHEMBL8744753 | 0.76 | CTSS (0.49) | MAPTKDM4ENPC1 | |
| SCHEMBL8744801 | 0.75 | NUDT1 (0.38) | USP8TLR8 | |
| SCHEMBL8744729 | 0.72 | KDM4E (0.46) | HSP90AB1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL11047513 | 0.72 | ALPL (0.42) | HSP90AB1MAPTKDM4EMEN1NPC1 | |
| SCHEMBL7142092 | 0.71 | MAPT (0.46) | MAPTKDM4EMEN1NPC1KMT2A | |
| SCHEMBL31218523 | 0.69 | TRPA1 (0.40) | ATM | |
| SCHEMBL8744748 | 0.68 | IDO1 (0.41) | MAPTKDM4ENPC1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653421-B1 | Process for preparing 2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA (JP) | 1997-01-15 | — | — | EP | disclosed |
| US-5552557-A | Process for preparing 2-cyanoimidazole compounds by reaction of an amino ketone compound | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1996-09-03 | — | — | US | disclosed |
| EP-0653421-A1 | Process for preparing 2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |