Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 6/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744751 | 1.00 | PYGL (0.48) | PYGLCYP2C9KMT2AGFERLMNA | |
| SCHEMBL9596067 | 0.86 | PYGL (0.38) | PYGLCYP2C9KMT2AGFERLMNA | |
| SCHEMBL8744770 | 0.86 | PYGL (0.38) | PYGLCYP2C9KMT2AGFERLMNA | |
| SCHEMBL8744704 | 0.85 | THRA (0.45) | PYGLCYP2C9KMT2AGFERPSMB5 | |
| SCHEMBL8744706 | 0.85 | THRA (0.45) | PYGLCYP2C9KMT2AGFERPSMB5 | |
| SCHEMBL8744757 | 0.83 | KMT2A (0.54) | PYGLCYP2C9KMT2AGFERL3MBTL1 | |
| SCHEMBL8744747 | 0.83 | KMT2A (0.54) | PYGLCYP2C9KMT2AGFERL3MBTL1 | |
| SCHEMBL7094315 | 0.80 | MAPK1 (0.44) | PYGLCYP2C9KMT2AGFERLMNA | |
| SCHEMBL7094314 | 0.80 | MAPK1 (0.44) | PYGLCYP2C9KMT2AGFERLMNA | |
| SCHEMBL9594891 | 0.80 | TAS1R3 (0.49) | CYP2C9KMT2ALMNAPSMB5THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456063-B1 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1997-01-22 | — | — | EP | disclosed |