Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12457771 | 0.88 | MAOA (0.38) | MAOAEGFRENPP2PTPRBTYR | |
| SCHEMBL9502006 | 0.79 | ENPP2 (0.51) | MAOAEGFRENPP2PTPRBTYR | |
| SCHEMBL13013083 | 0.74 | ALOX5 (0.41) | MAOAEGFRENPP2PTPRBTYR | |
| SCHEMBL10039964 | 0.74 | ALOX5 (0.38) | MAOAEGFRENPP2TYRALOX5 | |
| SCHEMBL10982120 | 0.73 | ALOX5 (0.42) | MAOAEGFRENPP2TYRALOX5 | |
| SCHEMBL7157597 | 0.72 | CYP3A4 (0.37) | EGFRALOX5PTGS2 | |
| SCHEMBL191427 | 0.71 | EGFR (0.38) | MAOAEGFRTYRALOX5MAPK1 | |
| SCHEMBL201692 | 0.70 | NPC1 (0.57) | EGFRTYRALOX5MAPK1PTGS2 | |
| SCHEMBL28050116 | 0.70 | S1PR1 (0.42) | EGFRTYRALOX5PTGS2 | |
| SCHEMBL28177157 | 0.69 | HMGCR (0.38) | MAOAEGFRENPP2TYRALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2042547-B1 | Benzocyclobutene based polymer formulations | DOW GLOBAL TECHNOLOGIES INC (US) | 2010-12-22 | — | — | EP | disclosed |
| EP-1802693-B1 | BENZOCYCLOBUTENE BASED POLYMER FORMULATIONS AND METHODS FOR PROCESSING SUCH FORMULATIONS IN OXIDATIVE ENVIRONMENTS | DOW GLOBAL TECHNOLOGIES INC (US) | 2010-08-04 | — | — | EP | disclosed |
| EP-2042547-A1 | Benzocyclobutene based polymer formulations | Dow Global Technologies Inc. (US) | 2009-04-01 | — | — | EP | disclosed |