SCHEMBL874506

SCHEMBL874506

CC(=O)c1ccc(N(O)C(C)=O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.50
RAB9A P51151 4/20 0.50
MAPK1 P28482 3/20 0.50
NPC1 O15118 3/20 0.50
KDM4E B2RXH2 1/20 0.50
HPGD P15428 4/20 0.46
KMT2A Q03164 2/20 0.46
LMNA P02545 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
SMN1; SMN2 Q16637 3/20 0.45
HSD17B1 P14061 1/20 0.45
GAA P10253 2/20 0.44
MEN1 O00255 1/20 0.44
POLB P06746 1/20 0.44
MCL1 Q07820 1/20 0.44
NOX1 Q9Y5S8 1/20 0.44
NOS3 P29474 2/20 0.42
NOS1 P29475 2/20 0.42
ALDH1A1 P00352 2/20 0.41
STAT3 P40763 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21679647 0.81 MAPT (0.53) MAPTRAB9AMAPK1NPC1KDM4E
SCHEMBL17681603 0.81 HPGD (0.52) MAPTRAB9AMAPK1NPC1KDM4E
SCHEMBL19483167 0.81 MAPT (0.50) MAPTRAB9AMAPK1NPC1KDM4E
SCHEMBL17671175 0.79 CA1 (0.53) MAPTRAB9AMAPK1NPC1KDM4E
SCHEMBL17671275 0.79 MAPT (0.47) MAPTRAB9AMAPK1NPC1KDM4E
SCHEMBL19483178 0.79 MAPT (0.45) MAPTRAB9AMAPK1NPC1KDM4E
SCHEMBL3279618 0.79 RAB9A (0.53) RAB9AKDM4EHPGDKMT2ALMNA
SCHEMBL874035 0.79 ALDH1A1 (0.41) MAPTRAB9ANPC1KDM4EHPGD
SCHEMBL8191180 0.78 MAPT (0.55) MAPTRAB9AMAPK1NPC1KDM4E
SCHEMBL19483180 0.78 HPGD (0.60) MAPTRAB9AMAPK1NPC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4727818-B2 2011-07-20 JP claimed
EP-1128730-B1 ANTIMICROBIAL COMPOSITION COMPRISING AN OXIDOREDUCTASE AND AN ENHANCING AGENT OF THE N-HYDROXYANILIDE-TYPE NOVOZYMES AS (DK) 2003-05-02 EP claimed
JP-2002529380-A 2002-09-10 JP claimed
US-20020094331-A1 ANTIMICROBIAL COMPOSITION CONTAINING AN OXIDOREDUCTASE AND AN ENHANCER OF THER N-HYDROXYANILIDE-TYPE NOVOZYMES A/S (DK) 2002-07-18 US claimed
EP-1128730-A1 ANTIMICROBIAL COMPOSITION COMPRISING AN OXIDOREDUCTASE AND AN ENHANCING AGENT OF THE N-HYDROXYANILIDE-TYPE Novozymes A/S (DK) 2001-09-05 EP claimed
WO-2000027204-A1 ANTIMICROBIAL COMPOSITION COMPRISING AN OXIDOREDUCTASE AND AN ENHANCING AGENT OF THE N-HYDROXYANILIDE-TYPE NOVOZYMES A/S (DK) 2000-05-18 WO claimed
EP-3444336-B1 CLEANING AGENT PROCTER & GAMBLE (US) 2024-05-08 EP disclosed
US-11724982-B2 Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2023-08-15 US disclosed
US-11724982-B2 Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2023-08-15 US disclosed
US-11724982-B2 Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2023-08-15 US disclosed
US-20210147765-A9 CLEANING KIT THE PROCTER AND GAMBLE COMPANY 2021-05-20 US disclosed
US-20210071117-A9 CLEANING AGENT THE PROCTER AND GAMBLE COMPANY 2021-03-11 US disclosed
US-20200262784-A1 TRIFLUOROMETHOXYLATION OF ARENES VIA INTRAMOLECULAR TRIFLUOROMETHOXY GROUP MIGRATION THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2020-08-20 US disclosed
WO-2001074980-A2 ENZYME TABLETS FOR CLEANING IMPROVEMENT NOVOZYMES A/S (DK) 2001-10-11 WO disclosed
EP-1128730-A1 ANTIMICROBIAL COMPOSITION COMPRISING AN OXIDOREDUCTASE AND AN ENHANCING AGENT OF THE N-HYDROXYANILIDE-TYPE Novozymes A/S (DK) 2001-09-05 EP disclosed
WO-2001048304-A1 PROCESS FOR REMOVAL OF EXCESS DISPERSE DYE FROM PRINTED OR DYED TEXTILE MATERIAL NOVOZYMES A/S (DK) 2001-07-05 WO disclosed
WO-2001023513-A1 PARTICLES FOR LIQUID COMPOSITIONS NOVOZYMES A/S (DK) 2001-04-05 WO disclosed
WO-2001010195-A1 REDUCTION OF MALODOUR IN SOILED ANIMAL LITTER NOVOZYMES A/S (DK) 2001-02-15 WO disclosed
WO-2000068324-A2 ENZYMATIC PRESERVATION OF WATER BASED PAINTS NOVOZYMES A/S (DK) 2000-11-16 WO disclosed
WO-2000027204-A1 ANTIMICROBIAL COMPOSITION COMPRISING AN OXIDOREDUCTASE AND AN ENHANCING AGENT OF THE N-HYDROXYANILIDE-TYPE NOVOZYMES A/S (DK) 2000-05-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094331-A1 ANTIMICROBIAL COMPOSITION CONTAINING AN OXIDOREDUCTASE AND AN ENHANCER OF THER N-HYDROXYANILIDE-TYPE LPO, MPO, LCT MAPT 2768/4885RAB9A 4091/4885MAPK1 4012/4885
US-20200262784-A1 TRIFLUOROMETHOXYLATION OF ARENES VIA INTRAMOLECULAR TRIFLUOROMETHOXY GROUP MIGRATION AHR, AFF2, AFF4 MAPT 3670/4885RAB9A 1219/4885MAPK1 3627/4885
US-11724982-B2 Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration AHR, AFF2, AFF4 MAPT 3670/4885RAB9A 1219/4885MAPK1 3627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.