SCHEMBL8745143

SCHEMBL8745143

C=Cc1ccc(CN(C)CCC(CCC(=O)O)C(=O)O)cc1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CPA3 P15088 1/20 0.40
KDM4A O75164 2/20 0.38
KDM4C Q9H3R0 2/20 0.38
KMT2A Q03164 2/20 0.37
ALDH1A1 P00352 1/20 0.37
GAA P10253 1/20 0.37
FOLH1 Q04609 7/20 0.36
AGTR2 P50052 1/20 0.35
DPP7 Q9UHL4 1/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21499733 0.79 KDM4A (0.55) KDM4AKDM4CKMT2AALDH1A1GAA
SCHEMBL8745187 0.78 CPA3 (0.66) CPA3FOLH1
SCHEMBL13958014 0.75 LTA4H (0.44) KMT2AAGTR2MEN1
SCHEMBL8745128 0.74 FOLH1 (0.45) CPA3FOLH1
SCHEMBL8745118 0.73 SMN1; SMN2 (0.44) KDM4AKDM4CKMT2AALDH1A1GAA
SCHEMBL18868390 0.71 SIGMAR1 (0.44) ALDH1A1
SCHEMBL6391713 0.71 PYCR1 (0.50) ALDH1A1
SCHEMBL18868380 0.70 PYCR1 (0.43) KMT2AALDH1A1MEN1
SCHEMBL9679480 0.70 PYCR1 (0.43) KMT2AALDH1A1MEN1
SCHEMBL18868383 0.69 PYCR1 (0.48) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0466220-B1 Carboxy containing monomers and polymers and latices prepared from same JOHNSON & JOHNSON CLIN DIAG (US) 1997-01-29 EP claimed
EP-0462670-B1 Use of 1-(1-pyrrolidinylcarbonyl)pyridinium salts to attach compounds to caboxylated particles & a kit containing same JOHNSON & JOHNSON CLIN DIAG (US) 1996-08-21 EP claimed
EP-0462644-B1 Biologically active reagents prepared from carboxy-containing polymer, analytical element and methods of use JOHNSON & JOHNSON CLIN DIAG (US) 1995-10-18 EP claimed