Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8747225 | 0.92 | AR (0.32) | ARTRPV4CYP11B1CYP11B2DRD2 | |
| SCHEMBL8745308 | 0.90 | AR (0.32) | ARTRPV4CYP11B1CYP11B2DRD2 | |
| SCHEMBL8745176 | 0.87 | NFE2L2 (0.36) | MAPTATM | |
| SCHEMBL8745260 | 0.83 | NFE2L2 (0.39) | MAPTATM | |
| SCHEMBL8745188 | 0.82 | PKM (0.30) | — | |
| SCHEMBL8745261 | 0.81 | TNNC1 (0.36) | MAPTDRD2DRD3 | |
| SCHEMBL9139977 | 0.80 | EPHX2 (0.34) | MAPTATM | |
| SCHEMBL8745378 | 0.79 | CYP2C9 (0.34) | MAPTARKDM1ATRPV4 | |
| SCHEMBL10345350 | 0.79 | DAO (0.40) | ARKDM1ATRPV4 | |
| SCHEMBL9620711 | 0.79 | DAO (0.40) | ARKDM1ATRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563981-B1 | Cis-1,4-substituted 2-butene derivative | CHISSO CORP (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5401434-A | Cis-1,4-substituted 2-butene derivative | CHISSO CORPORATION (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0563981-A2 | Cis-1,4-substituted 2-butene derivative | Chisso Corporation (JP) | 1993-10-06 | — | — | EP | disclosed |