Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3075110 | 0.87 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL2482183 | 0.87 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL977301 | 0.87 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL14155951 | 0.76 | MEN1 (0.37) | ALDH1A1MEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL9975511 | 0.72 | ALDH1A1 (0.37) | ALDH1A1MEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL27925964 | 0.71 | L3MBTL1 (0.37) | ALDH1A1MEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL13180821 | 0.69 | HTR2A (0.45) | ALDH1A1MEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL9732659 | 0.68 | KMT2A (0.38) | ALDH1A1MEN1KMT2AHPGDHSD17B10 | |
| SCHEMBL7074543 | 0.68 | PTPN22 (0.47) | ALDH1A1MEN1KMT2AHSD17B10KDM4E | |
| SCHEMBL29946603 | 0.68 | PTPN22 (0.47) | ALDH1A1MEN1KMT2AHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755382-A1 | QUINOLONE DERIVATIVE FOR TREATMENT OF URINARY INCONTINENCE | ZENECA LIMITED (GB) | 1997-01-29 | — | — | EP | disclosed |
| WO-1995028388-A1 | QUINOLONE DERIVATIVE FOR TREATMENT OF URINARY INCONTINENCE | ZENECA LIMITED (GB) | 1995-10-26 | — | — | WO | disclosed |