SCHEMBL288549

SCHEMBL288549

c1ccc(Pc2ccccc2Pc2ccccc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
CA12 O43570 1/20 0.37
GLA P06280 1/20 0.37
CA3 P07451 1/20 0.37
CA4 P22748 1/20 0.37
CA14 Q9ULX7 1/20 0.37
ALDH1A1 P00352 2/20 0.33
MMP3 P08254 1/20 0.30
BCL2L1 Q07817 1/20 0.30
TSHR P16473 3/20 0.30
LMNA P02545 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30
CA7 P43166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4061116 0.85 CA12 (0.32) CA1CA2CA9TDP1CA12
Benzene SCHEMBL28943358 0.82 TDP1 (0.44) CA1CA2CA9TDP1CA12
SCHEMBL49343 0.82 TDP1 (0.44) CA1CA2CA9TDP1CA12
Benzene SCHEMBL4445625 0.82 TDP1 (0.44) CA1CA2CA9TDP1CA12
SCHEMBL6551816 0.81
SCHEMBL9618209 0.81 ALDH1A1 (0.43) CA1CA2CA9TDP1CA12
SCHEMBL1516323 0.81 CA2 (0.43) CA1CA2CA9TDP1CA12
SCHEMBL22882956 0.81 ACHE (0.35) ALDH1A1TSHRACHE
SCHEMBL2933394 0.81 TSHR (0.43) CA1CA2CA9TDP1ALDH1A1
SCHEMBL8745400 0.81 TSHR (0.43) ALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024108774-A1 METAL-CATALYZED DOUBLE HYDROBORATION OF NITROGEN HETEROCYCLICS GUANGDONG TECHNION-ISRAEL INSTITUTE OF TECHNOLOGY (CN) 2024-05-30 WO claimed
EP-2850087-B1 BETA-BORATION OF ALKENE AND ALKYNE INTERMEDIATES LEK PHARMACEUTICALS (SI) 2017-08-02 EP claimed
CN-104603142-A Beta-boronation of alkene and alkyne intermediates LEK PHARMACEUTICALS 2015-05-06 CN claimed
CN-102414162-B Process for the preparation of vinyl esters from acetylene and carboxylic acids using homogeneous catalysts CELANESE INTERNATIONAL CORP. (US) 2014-10-29 CN claimed
EP-2427419-B1 VINYL ESTER PRODUCTION FROM ACETYLENE AND CARBOXYLIC UTILIZING HOMOGENEOUS CATALYST CELANESE INT CORP (US) 2014-06-18 EP claimed
EP-2647639-A1 ß-boration of alkene and alkyne intermediates LEK Pharmaceuticals d.d. (SI) 2013-10-09 EP claimed
EP-2647640-A1 ß-boration of alkene and alkyne intermediates LEK Pharmaceuticals d.d. (SI) 2013-10-09 EP claimed
US-8536367-B2 Vinyl ester production from acetylene and carboxylic acid utilizing homogeneous catalyst CELANESE INTERNATIONAL CORP. (US) 2013-09-17 US claimed
US-8173830-B2 For example, reacting acetyene and benzoic acid or neodecanoic acid to make vinyl benzoate or vinyl neodecanoate respectively on industrial scale using a iridium, palladium, platinum, or rhodium complex catalyst with use of certain ligands and additives CELANESE INTERNATIONAL CORPORATION (US) 2012-05-08 US claimed
CN-102421743-A Vinyl ester production from acetylene and carboxylic acid utilizing heterogeneous catalyst CELANESE INT CORP 2012-04-18 CN claimed
CN-102414162-A Process for the preparation of vinyl esters from acetylene and carboxylic acids using homogeneous catalysts CELANESE INT CORP 2012-04-11 CN claimed
EP-2427419-A2 VINYL ESTER PRODUCTION FROM ACETYLENE AND CARBOXYLIC UTILIZING HOMOGENEOUS CATALYST Celanese International Corporation (US) 2012-03-14 EP claimed
US-7982065-B2 Vinyl ester production from acetylene and carboxylic acid utilizing heterogeneous catalyst CELANESE INTERNATIONAL CORPORATION (US) 2011-07-19 US claimed
US-20100286441-A1 Vinyl Ester production from Acetylene and Carboxylic Acid utilizing heterogeneous catalyst CELANESE INTERNATIONAL CORPORATION 2010-11-11 US claimed
US-20100286440-A1 Vinyl Ester production from Acetylene and Carboxylic Acid utilizing homogeneous catalyst CELANESE INTERNATIONAL CORPORATION (US) 2010-11-11 US claimed
WO-2010129030-A2 VINYL ESTER PRODUCTION FROM ACETYLENE AND CARBOXYLIC UTILIZING HOMOGENEOUS CATALYST CELANESE INTERNATIONAL CORPORATION (US) 2010-11-11 WO claimed
EP-0128597-B1 ETHYLENE OLIGOMERIZATION PROCESS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-10-07 EP claimed
EP-0128596-B1 ETHYLENE OLIGOMERIZATION PROCESS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-05-20 EP claimed
WO-2024108774-A1 METAL-CATALYZED DOUBLE HYDROBORATION OF NITROGEN HETEROCYCLICS GUANGDONG TECHNION-ISRAEL INSTITUTE OF TECHNOLOGY (CN) 2024-05-30 WO disclosed
US-6084133-A REACTING A PHOSPHINE HALIDE WITH A METAL, THEN PROTONATION RESULTING DIORGANO-SUBSTITUTED METAL PHOSPHIDE; SIMPLIFICATION, NONTOXIC, EFFICIENCY KANKYO KAGAKU CENTER CO., LTD. (JP) 2000-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100286441-A1 Vinyl Ester production from Acetylene and Carboxylic Acid utilizing heterogeneous catalyst ACACA, ACACB, PCCA CA1 32/4885CA2 168/4885CA9 163/4885
US-20100286440-A1 Vinyl Ester production from Acetylene and Carboxylic Acid utilizing homogeneous catalyst ACACA, ACACB, ELL CA1 85/4885CA2 84/4885CA9 94/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.