Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 7/20 | 0.44 |
| ▸ | THRB | P10828 | 7/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | IL2 | P60568 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745433 | 0.86 | KMT2A (0.48) | KMT2AFPR2THRATHRBCA2 | |
| SCHEMBL8745406 | 0.86 | KMT2A (0.48) | KMT2AFPR2THRATHRBCA2 | |
| SCHEMBL8997459 | 0.83 | THRB (0.39) | FPR2THRATHRBALDH1A1ALOX15 | |
| SCHEMBL8745430 | 0.77 | PCNA (0.42) | THRATHRB | |
| SCHEMBL8745457 | 0.77 | THRB (0.61) | KMT2ATHRATHRBALDH1A1ALOX15 | |
| SCHEMBL7273788 | 0.76 | THRB (0.36) | KMT2ATHRATHRBALDH1A1 | |
| SCHEMBL8745463 | 0.75 | THRA (0.51) | THRATHRB | |
| SCHEMBL8047743 | 0.73 | THRB (0.60) | KMT2ATHRATHRBALDH1A1ALOX15 | |
| SCHEMBL8047744 | 0.73 | THRB (0.60) | KMT2ATHRATHRBALDH1A1ALOX15 | |
| SCHEMBL8745468 | 0.73 | FPR2 (0.49) | KMT2AFPR2CA2ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612308-B1 | METHOD FOR PREPARING RADIO-IODINATED THYRONINE DERIVATIVES; NOVEL INTERMEDIATES | HENNING BERLIN GMBH (DE) | 1997-02-05 | — | — | EP | disclosed |