Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143318 | 0.89 | — | — | |
| Sulfuric Acid SCHEMBL29647896 | 0.78 | ALOX15 (0.62) | GAARAB9AL3MBTL1SMN1; SMN2CA12 | |
| Sulfuric Acid SCHEMBL147075 | 0.78 | ALOX15 (0.62) | GAARAB9AL3MBTL1SMN1; SMN2CA12 | |
| Sulfuric Acid SCHEMBL29559847 | 0.76 | ALOX15 (0.59) | GAARAB9AL3MBTL1SMN1; SMN2CA12 | |
| Sulfuric Acid SCHEMBL1599591 | 0.76 | ALOX15 (0.59) | GAARAB9AL3MBTL1SMN1; SMN2CA12 | |
| Sulfuric Acid SCHEMBL9452067 | 0.74 | ALOX15 (0.56) | GAARAB9AL3MBTL1SMN1; SMN2CA12 | |
| SCHEMBL5888425 | 0.72 | GAA (0.59) | GAARAB9ANPC1L3MBTL1CA12 | |
| SCHEMBL5888431 | 0.72 | GAA (0.59) | GAARAB9ANPC1L3MBTL1CA12 | |
| SCHEMBL3870157 | 0.71 | MYC (0.41) | SMN1; SMN2TTRCYP1A2TSHRMAPT | |
| SCHEMBL24716112 | 0.71 | MMP2 (0.47) | GAARAB9ANPC1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621260-B1 | Process for producing N,N-disubstituted p-phenylenediamine derivative sulphate | WAKO PURE CHEM IND LTD (JP) | 1997-02-05 | — | — | EP | disclosed |
| US-5475140-A | Process for producing N,N-disubstituted p-phenylenediamine derivative sulfate | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-12 | — | — | US | disclosed |
| EP-0621260-A1 | Process for producing N,N-disubstituted p-phenylenediamine derivative sulphate | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1994-10-26 | — | — | EP | disclosed |