SCHEMBL8745525

SCHEMBL8745525

Cc1ccc(S(=O)(=O)CS(=O)(=O)c2ccc(C)c(O)c2)cc1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
HTT P42858 1/20 0.46
CA2 P00918 1/20 0.46
PLCG1 P19174 1/20 0.42
TSHR P16473 1/20 0.42
CASP1 P29466 1/20 0.42
GAA P10253 2/20 0.41
PKM P14618 1/20 0.41
SERPINE1 P05121 5/20 0.40
GFER P55789 1/20 0.40
ESR1 P03372 1/20 0.40
ACHE P22303 1/20 0.39
TRPA1 O75762 1/20 0.39
PTGS1 P23219 1/20 0.39
CACNA1C Q13936 1/20 0.39
LMNA P02545 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
MAPT P10636 1/20 0.39
HSD17B2 P37059 1/20 0.39
RAPGEF4 Q8WZA2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7083632 0.85 TSHR (0.44) ALDH1A1HTTCA2TSHRCASP1
SCHEMBL563388 0.81 ALDH1A1 (0.55) ALDH1A1TSHRCASP1GAAPKM
SCHEMBL8745509 0.81 ALDH1A1 (0.59) ALDH1A1HTTPLCG1TSHRGAA
SCHEMBL13204260 0.81 GAA (0.53) ALDH1A1TSHRCASP1GAAPKM
Water SCHEMBL2538022 0.79 ALDH1A1 (0.53) ALDH1A1TSHRCASP1GAAPKM
SCHEMBL26936872 0.79 ENPP2 (0.52) ALDH1A1TSHRCASP1GAAPKM
SCHEMBL6669968 0.79 CA2 (0.55) HTTCA2TSHRCASP1GAA
Hydrochloric Acid SCHEMBL28252264 0.79 ALDH1A1 (0.53) ALDH1A1TSHRCASP1GAAPKM
SCHEMBL5155863 0.79 TSHR (0.45) ALDH1A1TSHRCASP1GAAPKM
Ethylenediamine SCHEMBL11303876 0.77 ALDH1A1 (0.52) ALDH1A1CA2TSHRCASP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0654149-B1 POSITIVE-ACTING RADIATION-SENSITIVE MIXTURE AND RECORDING MATERIAL PRODUCED THEREWITH HOECHST AG (DE) 1997-02-05 EP disclosed