Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229260 | 0.82 | CXCR2 (0.38) | CXCR2CFD | |
| SCHEMBL6561841 | 0.79 | CXCR2 (0.40) | ALDH1A1CXCR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19258039 | 0.78 | NFKB1 (0.53) | CA1CA2GAAKMT2AL3MBTL1 | |
| SCHEMBL17696544 | 0.76 | PDK1 (0.36) | ALDH1A1CXCR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18025046 | 0.76 | CCR2 (0.39) | ALDH1A1CCR2NPC1HTTRAB9A | |
| SCHEMBL17696548 | 0.76 | PDK1 (0.36) | ALDH1A1CXCR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25072101 | 0.76 | CXCR2 (0.37) | CXCR2MAPTCFD | |
| SCHEMBL11036864 | 0.75 | CXCR2 (0.38) | CXCR2NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL18025052 | 0.75 | CCR2 (0.41) | ALDH1A1CCR2NPC1HTTRAB9A | |
| SCHEMBL9790031 | 0.74 | RAB9A (0.49) | ALDH1A1NPC1HTTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622916-A | PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| EP-0482410-B1 | Anti-microbial compounds, including substituted 2-cyclohexyl-amine derivatives and their preparation | BAYER AG (DE) | 1997-02-05 | — | — | EP | disclosed |
| US-5428073-A | Fungicide | BAYER AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |
| EP-0376072-B1 | Fungicidal and herbicidal agents and substituted 2-cyclohexen-1-yl amine derivatives, and their preparation | BAYER AG (DE) | 1994-02-16 | — | — | EP | disclosed |
| US-5270340-A | Substituted 2-cyclohexen-1-yl-amine fungicidal and herbicidal agents | BAYER AKTIENGESELLSCHAFT (DE) | 1993-12-14 | — | — | US | disclosed |
| US-5196441-A | COMPOUNDS USEFUL AS ANTIMICROBIAL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1993-03-23 | — | — | US | disclosed |
| EP-0482410-A2 | Anti-microbial compounds, including substituted 2-cyclohexyl-amine derivatives and their preparation | BAYER AG (DE) | 1992-04-29 | — | — | EP | disclosed |