Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | PTPRF | P10586 | 3/20 | 0.45 |
| ▸ | PTPRA | P18433 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874783 | 0.88 | IKBKB (0.48) | PTPN1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL875205 | 0.82 | PTPN1 (0.51) | PTPN1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL613433 | 0.79 | PTPN1 (0.48) | PTPN1MEN1KMT2APTPRFPTPRA | |
| SCHEMBL875026 | 0.76 | MAPT (0.53) | PTPN1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL2157667 | 0.75 | NPSR1 (0.63) | PTPN1MEN1KMT2APTPRF | |
| SCHEMBL2157723 | 0.74 | NPSR1 (0.50) | PTPN1MEN1KMT2A | |
| SCHEMBL874463 | 0.74 | RAB9A (0.65) | MEN1KMT2AMAPTRAB9AAPP | |
| SCHEMBL2158090 | 0.74 | MEN1 (0.50) | PTPN1MEN1KMT2AMAPT | |
| SCHEMBL7052069 | 0.72 | IKBKB (0.55) | PTPN1MEN1KMT2ARAB9AAPP | |
| SCHEMBL9206969 | 0.72 | MAPT (0.57) | MEN1KMT2AMAPTHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |