Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | GAA | P10253 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | JAK2 | O60674 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | MPI | P34949 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | SHBG | P04278 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19236367 | 0.86 | KDM4E (0.79) | KDM4EGAAMAPTMCL1SMN1; SMN2 | |
| SCHEMBL2791744 | 0.81 | GAA (0.67) | KDM4EGAAMAPTMCL1SMN1; SMN2 | |
| SCHEMBL31414410 | 0.81 | KDM4E (0.61) | KDM4EGAAMAPTMCL1SMN1; SMN2 | |
| SCHEMBL15285080 | 0.81 | KDM4E (0.61) | KDM4EGAAMAPTMCL1SMN1; SMN2 | |
| SCHEMBL2839705 | 0.79 | KDM4E (1.00) | KDM4EGAAMAPTMCL1SMN1; SMN2 | |
| SCHEMBL11216726 | 0.75 | KDM4E (0.60) | KDM4EGAAMAPTMCL1SMN1; SMN2 | |
| SCHEMBL28065536 | 0.75 | KDM4E (0.79) | KDM4EGAAMAPTMCL1SMN1; SMN2 | |
| SCHEMBL28065533 | 0.75 | KDM4E (0.56) | KDM4EGAAMAPTMCL1SMN1; SMN2 | |
| SCHEMBL28065504 | 0.75 | ESR2 (0.56) | KDM4EGAAMAPTMCL1SMN1; SMN2 | |
| SCHEMBL8745790 | 0.75 | KDM4E (0.68) | KDM4EGAAMAPTSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663911-B1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE | SCHWABE WILLMAR GMBH & CO (DE) | 1997-02-05 | — | — | EP | disclosed |
| US-5550129-A | THERAPY FOR NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | WILLMAR SCHWABE GMBH & CO. (DE) | 1996-08-27 | — | — | US | disclosed |
| EP-0663911-A1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE. | SCHWABE WILLMAR GMBH & CO (DE) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994008985-A1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1994-04-28 | — | — | WO | disclosed |