Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | PDE8B | O95263 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL526379 | 0.72 | CCR1 (0.39) | MEN1OPRM1OPRD1KMT2ASMN1; SMN2 | |
| SCHEMBL526380 | 0.72 | CCR1 (0.39) | MEN1OPRM1OPRD1KMT2ASMN1; SMN2 | |
| SCHEMBL2010535 | 0.67 | CCR1 (0.44) | MEN1OPRM1OPRD1KMT2ASMN1; SMN2 | |
| SCHEMBL882611 | 0.67 | HSP90AA1 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA4SMN1; SMN2 | |
| SCHEMBL4562212 | 0.67 | HSP90AA1 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA4SMN1; SMN2 | |
| SCHEMBL16097320 | 0.66 | MAPT (0.39) | MEN1OPRM1OPRD1KMT2ASMN1; SMN2 | |
| SCHEMBL17429701 | 0.66 | CCR1 (0.43) | CHRNB2CHRNB4CHRNA3CHRNA4MEN1 | |
| SCHEMBL247492 | 0.66 | SMN1; SMN2 (0.44) | MEN1OPRM1OPRD1KMT2ASMN1; SMN2 | |
| SCHEMBL13879249 | 0.64 | NOS2 (0.43) | MEN1OPRM1OPRD1KMT2ASMN1; SMN2 | |
| SCHEMBL27921519 | 0.64 | CHRNB2 (0.37) | CHRNB2CHRNB4CHRNA3CHRNA4GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638011-A1 | NOVEL MICROBIOCIDES | Syngenta Participations AG (CH) | 2013-09-18 | — | — | EP | disclosed |
| EP-2619181-A1 | NOVEL MICROBIOCIDES | Syngenta Participations AG (CH) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012062844-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012038521-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-03-29 | — | — | WO | disclosed |