Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 known ✓ | P09917 | 1/20 | 0.46 |
| ▸ | RAD51 | Q06609 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | LTA | P01374 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29829393 | 1.00 | ALOX5 (0.46) | ALOX5RAD51KDM4ENQO2ALDH1A1 | |
| SCHEMBL30430956 | 1.00 | ALOX5 (0.46) | ALOX5RAD51KDM4ENQO2ALDH1A1 | |
| SCHEMBL29434558 | 1.00 | ALOX5 (0.46) | ALOX5RAD51KDM4ENQO2ALDH1A1 | |
| SCHEMBL9241504 | 1.00 | ALOX5 (0.46) | ALOX5RAD51KDM4ENQO2ALDH1A1 | |
| SCHEMBL1502431 | 1.00 | ALOX5 (0.46) | ALOX5RAD51KDM4ENQO2ALDH1A1 | |
| SCHEMBL10789820 | 0.89 | RAD51 (0.38) | ALOX5RAD51KDM4EALDH1A1MAPT | |
| SCHEMBL1033597 | 0.88 | ALOX5 (0.46) | ALOX5KDM4ENQO2MAPTLMNA | |
| SCHEMBL31588309 | 0.88 | ALOX5 (0.46) | ALOX5KDM4ENQO2MAPTLMNA | |
| SCHEMBL1033598 | 0.88 | ALOX5 (0.46) | ALOX5KDM4ENQO2MAPTLMNA | |
| SCHEMBL31315043 | 0.88 | ALOX5 (0.46) | ALOX5KDM4ENQO2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 435 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200032171-A1 | Laundry Method, Use of Polypeptide and Detergent Composition | NOVOZYMES A/S (DK) | 2020-01-30 | — | — | US | claimed |
| EP-2427540-B1 | SHADING COMPOSITION | UNILEVER PLC (GB) | 2015-11-25 | — | — | EP | claimed |
| EP-0167205-B1 | STABLE LIQUID DETERGENTS CONTAINING ANIONIC SURFACTANT AND MONOSULFONATED BRIGHTENER | THE PROCTER & GAMBLE COMPANY (US) | 1992-03-11 | — | — | EP | claimed |
| US-4970029-A | MONOSULFONATED NAPHTHOTRIAZINE STILBENE BRIGHTENER | THE PROCTER & GAMBLE COMPANY (US) | 1990-11-13 | — | — | US | claimed |
| EP-0132138-B1 | FABRIC CONDITIONING COMPOSITION | UNILEVER PLC (GB) | 1990-05-09 | — | — | EP | claimed |
| EP-0075996-B1 | DETERGENT COMPOSITIONS CONTAINING ALKYLPOLYSACCHARIDE AND NONIONIC SURFACTANT MIXTURE AND ANIONIC OPTICAL BRIGHTENER | THE PROCTER & GAMBLE COMPANY (US) | 1987-01-21 | — | — | EP | claimed |
| EP-0167205-A2 | Stable liquid detergents containing anionic surfactant and monosulfonated brightener | THE PROCTER & GAMBLE COMPANY (US) | 1986-01-08 | — | — | EP | claimed |
| EP-0132138-A2 | Fabric conditioning composition | UNILEVER PLC (GB) | 1985-01-23 | — | — | EP | claimed |
| US-4483779-A | Detergent compositions comprising polyglycoside and polyethoxylate surfactants and anionic fluorescer | THE PROCTER & GAMBLE COMPANY (US) | 1984-11-20 | — | — | US | claimed |
| EP-0075996-A2 | Detergent compositions containing alkylpolysaccharide and nonionic surfactant mixture and anionic optical brightener | THE PROCTER & GAMBLE COMPANY (US) | 1983-04-06 | — | — | EP | claimed |
| EP-3607038-B1 | CLEANING COMPOSITIONS AND USES THEREOF | NOVOZYMES AS (DK) | 2026-05-06 | — | — | EP | disclosed |
| EP-3708660-B1 | POLYPEPTIDES | NOVOZYMES AS (DK) | 2026-04-29 | — | — | EP | disclosed |
| EP-3704220-B1 | METHODS FOR CLEANING MEDICAL DEVICES | NOVOZYMES AS (DK) | 2026-04-15 | — | — | EP | disclosed |
| US-12590273-B2 | Stabilized glycoside hydrolase variants | NOVOZYMES A/S (DK) | 2026-03-31 | — | — | US | disclosed |
| US-20260078359-A1 | POLYPEPTIDES | NOVOZYMES A/S (DK) | 2026-03-19 | — | — | US | disclosed |
| US-4483779-A | Detergent compositions comprising polyglycoside and polyethoxylate surfactants and anionic fluorescer | THE PROCTER & GAMBLE COMPANY (US) | 1984-11-20 | — | — | US | disclosed |
| EP-0075995-A2 | Detergent compositions containing mixtures of alkylpolysaccharide and nonionic surfactants | THE PROCTER & GAMBLE COMPANY (US) | 1983-04-06 | — | — | EP | disclosed |
| EP-0075994-A2 | Detergent compositions containing mixture of alkylpolysaccharide and amine oxide surfactants and fatty acid soap | THE PROCTER & GAMBLE COMPANY (US) | 1983-04-06 | — | — | EP | disclosed |
| EP-0075996-A2 | Detergent compositions containing alkylpolysaccharide and nonionic surfactant mixture and anionic optical brightener | THE PROCTER & GAMBLE COMPANY (US) | 1983-04-06 | — | — | EP | disclosed |
| US-4303701-A | IMPREGNATING WITH A FLUORESCENT MATERIAL | BUCKBEE-MEARS COMPANY (US) | 1981-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12590273-B2 | Stabilized glycoside hydrolase variants | IDUA, IDE, TREH | ALOX5 3981/4885RAD51 3874/4885KDM4E 1626/4885 |
| US-20260078359-A1 | POLYPEPTIDES | IDUA, IDE, AGL | ALOX5 3273/4885RAD51 1057/4885KDM4E 1629/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.