Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.46 |
| ▸ | PARP1 | P09874 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.39 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GUSB | P08236 | 2/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL379982 | 0.89 | PARP1 (0.48) | TNKS2PARP1ALDH1A1PDPK1CA12 | |
| SCHEMBL30067279 | 0.89 | PARP1 (0.48) | TNKS2PARP1ALDH1A1PDPK1CA12 | |
| Hydrochloric Acid SCHEMBL5807955 | 0.87 | PARP1 (0.47) | TNKS2PARP1ALDH1A1PDPK1CA12 | |
| SCHEMBL29262564 | 0.73 | PARP1 (0.36) | TNKS2PARP1ALDH1A1PDPK1CA12 | |
| SCHEMBL9483856 | 0.72 | IP6K1 (0.38) | PARP1KMT2A | |
| Bromoethane SCHEMBL874658 | 0.72 | CYP1A2 (0.42) | TNKS2ALDH1A1KDM4EPDPK1SMN1; SMN2 | |
| SCHEMBL13252170 | 0.71 | TNKS2 (0.46) | TNKS2PARP1ALDH1A1KDM4EPDPK1 | |
| SCHEMBL874742 | 0.68 | PARP1 (0.54) | TNKS2PARP1ALDH1A1KDM4EELANE | |
| SCHEMBL38658683 | 0.68 | METAP2 (0.43) | TNKS2PDPK1TNKSPRMT5 | |
| SCHEMBL10987574 | 0.68 | METAP2 (0.43) | TNKS2PDPK1TNKSPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140148459-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2014-05-29 | — | — | US | disclosed |
| EP-2619185-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038942-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148459-A1 | MATRIX METALLOPROTEINASE INHIBITORS | MMP9, MMP12, MMP10 | TNKS2 1948/4885PARP1 462/4885ALDH1A1 2281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.