SCHEMBL379982

SCHEMBL379982

O=c1[nH]nnc2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 5/20 0.48
TNKS2 Q9H2K2 5/20 0.48
ALOX15 P16050 2/20 0.48
PDPK1 O15530 1/20 0.48
CA12 O43570 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CA9 Q16790 1/20 0.48
GPR3 P46089 1/20 0.48
QTRT1 Q9BXR0 1/20 0.46
TNKS O95271 2/20 0.44
ALDH1A1 P00352 2/20 0.44
HSD17B10 Q99714 2/20 0.44
PRKCI P41743 1/20 0.44
PDE4B Q07343 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ATM Q13315 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
PKM P14618 1/20 0.42
KMT2A Q03164 1/20 0.41
PRMT5 O14744 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30067279 1.00 PARP1 (0.48) PARP1TNKS2ALOX15PDPK1CA12
Hydrochloric Acid SCHEMBL5807955 0.98 PARP1 (0.47) PARP1TNKS2ALOX15PDPK1CA12
Bromoethane SCHEMBL874659 0.89 TNKS2 (0.46) PARP1TNKS2ALOX15PDPK1CA12
SCHEMBL29262564 0.82 PARP1 (0.36) PARP1TNKS2ALOX15PDPK1CA12
SCHEMBL13252170 0.79 TNKS2 (0.46) PARP1TNKS2ALOX15PDPK1CA12
SCHEMBL10639619 0.76 MAPT (0.53) PARP1SMN1; SMN2ALDH1A1HSD17B10PRKCI
SCHEMBL28953289 0.76 PRMT5 (0.49) PARP1TNKS2SMN1; SMN2TNKSALDH1A1
SCHEMBL7114862 0.74 GPR3 (0.48) PARP1TNKS2SMN1; SMN2GPR3TNKS
SCHEMBL3759284 0.74 HCAR2 (0.46) PARP1ALDH1A1HSD17B10PRKCIPDE4B
SCHEMBL17950454 0.73 MAOA (0.43) SMN1; SMN2HSD17B10TDP1TUBB4ATUBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 607 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12532631-B2 Electronic apparatus and method of manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2026-01-20 US claimed
CN-119874631-A Synthesis method of 1,2, 3-benzotriazine-4-ketone 河北凯诺中星科技有限公司 2025-04-25 CN claimed
CN-119661459-A 1,2, 3-Benzotriazine-4 (3H) -one seleno compound and preparation method and application thereof 赣南师范大学 2025-03-21 CN claimed
CN-119506909-A Method for electrochemically synthesizing 3, 4-dihydro-isoquinoline-1 (2H) -ketone compound 宜宾学院 2025-02-25 CN claimed
CN-119343341-A Compound for inhibiting or degrading Bcl6 and application of compound in medicine 西藏海思科制药有限公司 2025-01-21 CN claimed
US-12127426-B2 Heterocyclic compound and electronic apparatus SAMSUNG DISPLAY CO., LTD. (KR) 2024-10-22 US claimed
US-20240252488-A1 MLKL BINDING OR DEGRADING COMPOUND AND PHARMACEUTICAL USE THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2024-08-01 US claimed
CN-114497728-B Electrolyte, electrochemical device and electronic device 宁德新能源科技有限公司 2024-06-11 CN claimed
CN-117987193-A Bentonite grease and preparation method thereof 中国石油化工股份有限公司 2024-05-07 CN claimed
CN-117965228-A Composite lithium-based lubricating grease and preparation method thereof 中国石油化工股份有限公司 2024-05-03 CN claimed
EP-0065477-B1 COMPOSITE OF RUBBER AND METAL REINFORCEMENT THEREFOR THE GOODYEAR TIRE & RUBBER COMPANY (US) 1986-07-23 EP claimed
EP-0107536-B1 BENZO- AND THIENO-1,2,3-TRIAZIN-4-ONES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1986-05-28 EP claimed
US-4585734-A Photothermographic toners MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1986-04-29 US claimed
EP-0108352-B1 3-(3-IODOPROPARGYL)-BENZO-1,2,3-TRIAZIN-4-ONES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION AS MICROBICIDES BAYER AG (DE) 1986-04-02 EP claimed
EP-0061986-B1 COATED FILAMENT AND COMPOSITE THEREOF WITH RUBBER THE GOODYEAR TIRE & RUBBER COMPANY (US) 1985-08-21 EP claimed
EP-0108352-A2 3-(3-Iodopropargyl)-benzo-1,2,3-triazin-4-ones, process for their preparation and their application as microbicides BAYER AG (DE) 1984-05-16 EP claimed
US-4391318-A CONTAINS CYANURIC DERIVATIVE, FOR TIRES, BELTS AND HOSES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1983-07-05 US claimed
EP-0065477-A1 Composite of rubber and metal reinforcement therefor THE GOODYEAR TIRE & RUBBER COMPANY (US) 1982-11-24 EP claimed
US-4138263-A Photographic silver halide material with 2-equivalent, N-heterocyclic yellow couplers AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) 1979-02-06 US claimed
US-4019909-A BLOWING AGENT E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-04-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240252488-A1 MLKL BINDING OR DEGRADING COMPOUND AND PHARMACEUTICAL USE THEREOF MLKL, PCSK9, CTSA PARP1 704/4885TNKS2 896/4885ALOX15 1338/4885
US-12127426-B2 Heterocyclic compound and electronic apparatus ERCC4, ERCC1, ESD PARP1 1044/4885TNKS2 2505/4885ALOX15 738/4885
US-12532631-B2 Electronic apparatus and method of manufacturing the same SRMS, LRRK2, TEC PARP1 540/4885TNKS2 690/4885ALOX15 1672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.