Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CDC7 | O00311 | 5/20 | 0.49 |
| ▸ | DBF4 | Q9UBU7 | 5/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874741 | 0.83 | KMT2A (0.48) | RAB9AMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL874528 | 0.78 | RAB9A (0.72) | RAB9AMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL874739 | 0.77 | RAB9A (0.71) | RAB9AMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL8867718 | 0.77 | RAB9A (1.00) | RAB9AMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL11280392 | 0.74 | MAPT (0.67) | RAB9AMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL24726553 | 0.72 | APP (0.52) | RAB9AALDH1A1APPPOLBMAPT | |
| SCHEMBL10909889 | 0.71 | MAPT (0.62) | RAB9AMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL874463 | 0.71 | RAB9A (0.65) | RAB9AMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL874100 | 0.70 | RAB9A (0.64) | RAB9AMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL15176802 | 0.70 | CDC7 (0.70) | RAB9AMEN1ALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |