Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | IDH2 | P48735 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 2/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874429 | 0.85 | CDC7 (0.42) | ALDH1A1MAPTRAB9ACDC7DBF4 | |
| SCHEMBL874800 | 0.83 | RAB9A (0.62) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPT | |
| SCHEMBL874757 | 0.71 | HDAC1 (0.44) | — | |
| SCHEMBL30583813 | 0.67 | NPC1 (0.57) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPT | |
| SCHEMBL28975685 | 0.67 | NPC1 (0.57) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPT | |
| SCHEMBL30583812 | 0.67 | NPC1 (0.57) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPT | |
| SCHEMBL24726553 | 0.66 | APP (0.52) | ALDH1A1MAPTRAB9APOLBAPP | |
| SCHEMBL18458068 | 0.66 | POLB (0.56) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPT | |
| SCHEMBL10909889 | 0.66 | MAPT (0.62) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPT | |
| SCHEMBL874528 | 0.64 | RAB9A (0.72) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |