Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGB1 | P09429 | 1/20 | 0.59 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | ME2 | P23368 | 1/20 | 0.43 |
| ▸ | ME1 | P48163 | 1/20 | 0.43 |
| ▸ | ME3 | Q16798 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3422904 | 0.80 | THRB (0.57) | HMGB1KDM4EMEN1ALDH1A1CYP1A2 | |
| SCHEMBL8747572 | 0.77 | ALDH1A1 (0.42) | HMGB1CXCL12MEN1ALDH1A1HPGD | |
| SCHEMBL27571871 | 0.77 | THRB (0.58) | HMGB1CXCL12KDM4EMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7535914 | 0.76 | THRB (0.56) | HMGB1CXCL12KDM4EMEN1ALDH1A1 | |
| SCHEMBL28256436 | 0.76 | HPGD (0.47) | HMGB1CXCL12KDM4EMEN1ALDH1A1 | |
| SCHEMBL8747580 | 0.74 | HMGB1 (1.00) | HMGB1CXCL12KDM4EMEN1ALDH1A1 | |
| SCHEMBL7886849 | 0.74 | HMGB1 (0.58) | HMGB1CXCL12MEN1KMT2ABCL2L1 | |
| SCHEMBL4731723 | 0.73 | ME2 (0.73) | HMGB1CXCL12KDM4EMEN1ALDH1A1 | |
| SCHEMBL29599456 | 0.72 | KDM4E (0.68) | KDM4EMEN1ALDH1A1CYP1A2GLA | |
| SCHEMBL70004 | 0.72 | KDM4E (0.68) | KDM4EMEN1ALDH1A1CYP1A2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0490370-B1 | Electrostatic image-developing toner | MITSUBISHI CHEM CORP (JP) | 1997-03-12 | — | — | EP | disclosed |
| US-5200288-A | Mixture of resin, colorant and additive having constant changeability | MITSUBISHI KASEI CORPORATION (JP) | 1993-04-06 | — | — | US | disclosed |
| EP-0490370-A1 | Electrostatic image-developing toner | Mitsubishi Chemical Corporation (JP) | 1992-06-17 | — | — | EP | disclosed |