Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8747855 | 0.78 | — | — | |
| SCHEMBL8748112 | 0.75 | CYP4A11 (0.41) | GAAMAPT | |
| SCHEMBL29268068 | 0.70 | L3MBTL1 (0.40) | L3MBTL1LMNAGAAMAPTHTT | |
| SCHEMBL2154504 | 0.67 | KMT2A (0.47) | L3MBTL1LMNAGAAMAPTHTT | |
| SCHEMBL9250153 | 0.67 | SLC16A3 (0.35) | — | |
| SCHEMBL25801684 | 0.67 | L3MBTL1 (0.39) | L3MBTL1LMNAGAAMAPTHTT | |
| SCHEMBL9247339 | 0.66 | ALDH1A1 (0.35) | GAANPC1RAB9A | |
| 3-Methoxyphenylacetonitrile SCHEMBL103029 | 0.65 | PKM (0.61) | LMNAGAAMAPTPKMNPC1 | |
| SCHEMBL28001771 | 0.65 | PKM (0.41) | L3MBTL1GAAMAPTPKMNPC1 | |
| SCHEMBL9313131 | 0.65 | NPC1 (0.39) | L3MBTL1MAPTPKMNPC1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0599732-B1 | Derivatives of 1-phenylbicyclo-2,2,2-octane, their preparation process and pharmaceutical compositions containing them | ADIR (FR) | 1997-03-12 | — | — | EP | disclosed |
| US-5403953-A | Antiarthritic and -inflammatory agents | ADIR ET COMPAGNIE (FR) | 1995-04-04 | — | — | US | disclosed |
| EP-0599732-A1 | Derivatives of 1-phenylbicyclo-2,2,2-octane, their preparation process and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-06-01 | — | — | EP | disclosed |